Balekudru Jaya Devadas from 2175 Parasol Dr, Wildwood, MO 63017, age 73

Us Patents

Sulfonylalkanoylamino Hydroxyethylamino Sulfonamide Retroviral Protease Inhibitors
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US Patent:

6380188, Apr 30, 2002
Filed:

Sep 29, 2000
Appl. No.:

09/672449
Inventors:

Daniel P. Getman - Chesterfield MO
Gary A. DeCrescenzo - St. Charles MO
John N. Freskos - Clayton MO
Michael L. Vazquez - Gurnee IL
James A. Sikorski - Des Peres MO
Balekudru Devadas - Chesterfield MO
Joseph J. McDonald - Ballwin MO
Assignee:

G. D. Searle Co. - Chicago IL
International Classification:

A61K 31343
US Classification:

5142282, 514367, 514375, 514464, 514469, 544135, 544137, 546196, 546198, 548178, 548217, 548517, 548518, 549434, 549438, 549467
Abstract:

Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.

Bis-Amino Acid Hydroxyethylamino Sulfonamide Retroviral Protease Inhibitors
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US Patent:

6388132, May 14, 2002
Filed:

Oct 24, 2000
Appl. No.:

09/694783
Inventors:

Daniel P Getman - Chesterfield MO
Gary A DeCrescenzo - St. Peters MO
John N Freskos - Clayton MO
Michael L Vazquez - Ballwin MO
James A Sikorski - Des Peres MO
Balekudru Devadas - Chesterfield MO
Srinivasan Raj Nagarajan - Chesterfield MO
David L Brown - Chesterfield MO
Joseph J McDonald - Ballwin MO
Assignee:

G. D. Searle Co. - Chicago IL
International Classification:

C07C31103
US Classification:

564 92, 564 90, 514604
Abstract:

Selected bis-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.

Heterocyclecarbonyl Amino Acid Hydroxyethylamino Sulfonamide Retroviral Protease Inhibitors
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US Patent:

6407134, Jun 18, 2002
Filed:

Feb 5, 2001
Appl. No.:

09/775682
Inventors:

Daniel P Getman - Chesterfield MO
Gary A DeCrescenzo - St. Peters MO
John N Freskos - Clayton MO
Michael L Vazquez - Gurnee MO
James A Sikorski - Des Peres MO
Balekudru Devadas - Chesterfield MO
Srinivasan Nagarajan - Chesterfield MO
David L Brown - Chesterfield MO
Joseph J McDonald - Ballwin MO
Assignee:

G. D. Searle Co. - Chicago IL
International Classification:

A61K 314025
US Classification:

514422, 548526
Abstract:

Selected heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.

Pyrazole Substituted Hydroxamic Acid Derivatives As Cyclooxygenase-2 And 5-Lipoxygenase Inhibitors
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US Patent:

6432999, Aug 13, 2002
Filed:

Jun 11, 2001
Appl. No.:

09/878538
Inventors:

John J Talley - St. Louis MO
James A Sikorski - Des Peres MO
Matthew J Graneto - Chesterfield MO
Jeffrey S Carter - Chesterfield MO
Bryan H Norman - Indianapolis IN
Balekudru Devadas - Chesterfield MO
Assignee:

Pharmacia Corporation - St.Louis MO
International Classification:

A61K 31415
US Classification:

514406, 5483751
Abstract:

This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation.

Amino Acid Hydroxyethylamino Sulfonamide Retroviral Protease Inhibitors
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US Patent:

6458785, Oct 1, 2002
Filed:

Apr 18, 2001
Appl. No.:

09/836443
Inventors:

Daniel P Getman - Chesterfield MO
Gary A. DeCrescenzo - St. Peters MO
John N. Freskos - Clayton MO
Michael L. Vazquez - Ballwin MO
James A. Sikorski - Des Peres MO
Balekudru Devadas - Chesterfield MO
Srinivasan Nagarajan - Chesterfield MO
David L. Brown - Chesterfield MO
Joseph J. McDonald - Ballwin MO
Assignee:

G. D. Searle - Chicago IL
International Classification:

A61K 3154
US Classification:

5142282, 5142338, 514321, 514322, 514324, 544 62, 544129, 546197, 546198, 546199
Abstract:

Selected amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.

Substituted Benzopyran Analogs For The Treatment Of Inflammation
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US Patent:

6492390, Dec 10, 2002
Filed:

May 24, 2001
Appl. No.:

09/865177
Inventors:

Jeffery S Carter - Chesterfield MO
Mark G Obukowicz - Kirkwood MO
Balekudru Devadas - Chesterfield MO
John J Talley - St. Louis MO
David L Brown - Chesterfield MO
Matthew J Graneto - Chesterfield MO
Stephen R Bertenshaw - Cheshire CT
Srinivasan Raj Nagarajan - Chesterfield MO
Cathleen E Hanau - St. Louis MO
Susan J Hartmann - Kirkwood MO
Cindy L Ludwig - St. Louis MO
Suzanne Metz - Chesterfield MO
Donald E Korte - Mundelein IL
Assignee:

G.D. Searle Co. - Chicago IL
International Classification:

A61K 3138
US Classification:

514311, 514432, 514456, 514569, 546170, 549 57, 549405, 562490
Abstract:

A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula Iâ wherein X, A , A , A , A , R, Râ, R and R are as described in the specification.

Heterocyclo Substituted Hydroxamic Acid Derivatives As Cyclooxygenase-2 And 5-Lipoxygenase Inhibitors
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US Patent:

6512121, Jan 28, 2003
Filed:

Jun 11, 2001
Appl. No.:

09/878452
Inventors:

John J Talley - St. Louis MO
James A Sikorski - Des Peres MO
Matthew J Graneto - Chesterfield MO
Jeffrey S Carter - Chesterfield MO
Bryan H Norman - Indianapolis IN
Balekudru Devadas - Chesterfield MO
Assignee:

G.D. Searle Co. - Skokie IL
International Classification:

C07D26332
US Classification:

548111, 546332, 546337, 548204, 548214, 548236, 548247, 5483381, 548561, 549496, 562621, 562623
Abstract:

This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation.

Thiophene Substituted Hydroxamic Acid Derivatives As Cyclooxygenase-2 And 5-Lipoxygenase Inhibitors
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US Patent:

6515014, Feb 4, 2003
Filed:

Jun 11, 2001
Appl. No.:

09/878496
Inventors:

John J Talley - St. Louis MO
James A Sikorski - Des Peres MO
Matthew J Graneto - Chesterfield MO
Jeffrey S Carter - Chesterfield MO
Bryan H Norman - Indianapolis IN
Balekudru Devadas - Chesterfield MO
Assignee:

G. D. Searle Co. - Chicago IL
International Classification:

C07D33324
US Classification:

514438, 549 77
Abstract:

This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to compounds, compositions and methods for treating disorders mediated by cyclooxygenase-2 or 5-lipoxygenase, such as inflammation.

Resumes

Balekudru Devadas Chesterfield, MO

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Work:

Confluence Life sciences Inc
St. Louis, MO
2010 to 2012
Science Research Fellow Pfizer
St. Louis, MO
2004 to 2010
Associate Fellow Pharmacia, St. Louis, MO
St. Louis, MO
1999 to 2004
Research Advisor G. D. Searle
St. Louis, MO
1996 to 1999
RESEARCH SCIENTIST II G. D. Searle
St. Louis, MO
1994 to 1995
RESEARCH SCIENTIST I Monsanto
St. Louis, MO
1991 to 1993
Research Specialist Monsanto
St. Louis, MO
1987 to 1990
SENIOR RESEARCH CHEMIST Univ. of Illinois
Urbana, IL
1985 to 1987
Postdoctoral Research Associate Prof. J. P. Ferris
Troy, NY
1981 to 1984
Postdoctoral Research Associate

Education:

Central Drug Research Institute
1980
Ph. D. in Chemistry

Skills:

Structure-based Drug Design, Multiparameter lead optimization, SAR-analysis, process development, Total synthesis, HPLC, NMR,Mass spectromery,and computer skills,and people mangement skills