Brendi M Cumberland

US Patent:

7968348, Jun 28, 2011

Filed:

Nov 20, 2008

Appl. No.:

12/274923

Inventors:

Brendi M. Cumberland - Pleasanton CA, US
Maha El-Sayed - Pleasanton CA, US
Alan J. Fujii - Santa Ana CA, US
Scott D Manske - Pleasanton CA, US
Elias A. Shaheen - Pleasanton CA, US

Assignee:

The Clorox Company - Oakland CA

International Classification:

G01N 33/53

US Classification:

436514, 436518, 977700, 977773, 977788, 977918, 422400, 422405, 422406, 422408, 422413, 422420, 422425, 422430

Abstract:

Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base. The wick transfers at least a portion of analyte and the elution solvent to the lateral flow strip for the colorimetric detection of specific allergens, viruses, bacteria, and other protein containing substances in the sample.

US Patent:

20050287616, Dec 29, 2005

Filed:

Jun 29, 2004

Appl. No.:

10/880783

Inventors:

Adam Gross - Pleasanton CA, US
Brendi Cumberland - Pleasanton CA, US
Kelly Dickson - Pleasanton CA, US
Steven Bromberg - Pleasanton CA, US

International Classification:

G01N033/53
G01N033/542
G01N033/537

US Classification:

435007920

Abstract:

The present invention encompasses a method for performing an antibody-antigen assay using an ion-exchange technique prior to performing an antibody-antigen assay. Actives from protein-denaturing solutions are physically removed from the test sample, preferably by using an ion-exchange resin. The present invention also includes a method of performing an antibody-antigen assay, which does not use coating antibody on the sample holder. These methods for removing or eliminating interferences can be used in an ELISA to more effectively, efficiently and promptly screen formulations containing protein-denaturing compounds for efficacy against proteins in common allergens and detect and quantify such proteins.

US Patent:

20070231923, Oct 4, 2007

Filed:

Apr 3, 2006

Appl. No.:

11/397522

Inventors:

Brendi Cumberland - Pleasanton CA, US
Maha El-Sayed - Pleasanton CA, US
Alan Fujii - Newport Beach CA, US
Scott Manske - Pleasanton CA, US
Elias Shaheen - Pleasanton CA, US

International Classification:

G01N 33/558

US Classification:

436514000

Abstract:

Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base. The wick transfers at least a portion of analyte and the elution solvent to the lateral flow strip for the calorimetric detection of specific allergens, viruses, bacteria, and other protein containing substances in the sample. The colorimetric results of the test are displayed through a window in the base.

US Patent:

20080003144, Jan 3, 2008

Filed:

Jun 29, 2006

Appl. No.:

11/427469

Inventors:

Brendi M. Cumberland - Pleasanton CA, US
Alan J. Fujii - Newport Beach CA, US
Scott D. Manske - Pleasanton CA, US
Elias A. Shaheen - Danville CA, US

International Classification:

B01L 3/00

US Classification:

422 99

Abstract:

Provided is sampling device and method for the detection of an analyte of interest on an environmental surface. The sampling device includes a first reservoir adapted to contain a first liquid, a second reservoir adapted to contain a second liquid, a swab holder coupled to the first reservoir and the second reservoir, a swab disposed within the swab holder, and an activation member coupled to the first and second reservoirs opposite the swab holder. After the swab is used to collect a sample from an environmental surface, and upon application of an activation force on the activation member, the first and second reservoirs are placed in fluid communication with the swab holder and the first and second liquids flow into the swab holder to contact the swab. The swab develops an indicator color if the sample of the environmental surface contained the analyte of interest.