Alana A Benn

US Patent:

20130071852, Mar 21, 2013

Filed:

Oct 12, 2012

Appl. No.:

13/651112

Inventors:

Life Technologies Corporation - Carlsbad CA, US
Alana BENN - Pleasanton CA, US
Jerry BOONYARATANAKORNKIT - Davis CA, US
Mona Danielle SHAHBAZIAN - Martinez CA, US

Assignee:

Life Technologies Corporation - Carlsbad CA

International Classification:

C12Q 1/68
C12N 1/20

US Classification:

435 612, 4352521

Abstract:

The invention relates to the quality control of testing using nucleic acid amplification-based detection assays. A control containing a quantified amount of the microorganism with high reproducibility across vials and which is used to calibrate, validate, or verify the performance of an MRSA detection assay and methods to test patient samples together with a control. Disclosed are specific strains that have a phenotype demonstrating reduced aggregation and increased consistency by Real-Time PCR compared to current strains used as external controls. Also disclosed is a process for increasing the reproducibility of strains that do not exhibit a non-aggregating phenotype.

US Patent:

20090197275, Aug 6, 2009

Filed:

Feb 6, 2009

Appl. No.:

12/367432

Inventors:

Erhard Ralf Schoenbrunner - Moraga CA, US
Alana Benn - Pleasanton CA, US
Mona Shahbazian - Concord CA, US

International Classification:

C12Q 1/68
C12N 1/20

US Classification:

435 6, 4352521

Abstract:

The invention relates to the quality control of testing using nucleic acid amplification-based detection assays. A control containing a quantified amount of the microorganism with high reproducibility across vials and which is used to calibrate, validate, or verify the performance of an MRSA detection assay and methods to test patient samples together with a control. Disclosed are specific strains that have a phenotype demonstrating reduced aggregation and increased consistency by Real-Time PCR compared to current strains used as external controls. Also disclosed is a process for increasing the reproducibility of strains that do not exhibit a non-aggregating phenotype.