Zara Weng Sieh

US Patent:

20060226575, Oct 12, 2006

Filed:

Apr 7, 2005

Appl. No.:

11/100751

Inventors:

Mariam Maghribi - Fremont CA, US
Zara Sieh - Pleasanton CA, US

International Classification:

B29C 41/02
B29C 59/02
B29C 71/02
B28B 11/08
B28B 7/14
B29C 71/00

US Classification:

264293000, 264163000, 264236000

Abstract:

Various methods of micro-fabricating 2-dimensional and 3-dimensional medical devices comprised of bio-degradable materials. The various methods use conventional photo-lithographic techniques commonly used in the semi-conductor or integrated circuit industry and translate those techniques to process bio-degradable medical devices. The devices may be active, passive or combination active-passive devices for controlling the release of drugs or other bio-active agents contained within the devices. Such devices may be used externally or internally for drug delivery, wound healing, tissue re-generation or the like.

US Patent:

20070066939, Mar 22, 2007

Filed:

Sep 18, 2006

Appl. No.:

11/532587

Inventors:

Peter Krulevitch - Pleasanton CA, US
William Benett - Livermore CA, US
Neil Roberts - Pleasanton CA, US
Sebastian Bohm - Los Gatos CA, US
Zara Sieh - Pleasanton CA, US

Assignee:

LifeScan, Inc. - Milpitas CA

International Classification:

A61M 1/00

US Classification:

604152000

Abstract:

Various methods and devices are provided for delivering an infusion liquid using an electrokinetic infusion pump. The electrokinetic infusion pump can generally include an infusion housing having an infusion reservoir. The infusion reservoir has an infusion outlet and is capable of containing an infusion liquid. A plunger is movably coupled to the infusion housing and is adapted to be manually displaced relative to the infusion housing to load the infusion reservoir with infusion liquid. A movable partition can be disposed within the infusion housing and has a first surface in communication with an electrokinetic solution and a second surface, isolated from the first surface, in communication with the infusion reservoir. The electrokinetic infusion pump can further include an electrokinetic engine integrated within the plunger and adapted to selectively deliver electric potential across an electrokinetic porous media to cause the electrokinetic solution within the electrokinetic engine to displace the movable partition to effect delivery of at least a portion of the infusion liquid through the infusion outlet.

US Patent:

20070129620, Jun 7, 2007

Filed:

Dec 2, 2005

Appl. No.:

11/293754

Inventors:

Peter Krulevitch - Pleasanton CA, US
Sharbel Noujaim - Menlo Park CA, US
Zara Sieh - Pleasanton CA, US

International Classification:

A61B 5/05
A61B 17/20
A61B 5/00

US Classification:

600347000, 600365000, 604046000

Abstract:

A medical detecting device including at least one miniature probe/lance (hereinafter microprotrusion) containing an integrated sensor which is covered with a protective coating to shield the sensor from fouling and other interactions with a host prior to its desired use is provided. In accordance with the present invention, the protective coating is selectively removed from the sensor prior to using the same. The present invention also provides a method for detecting a selected agent using the medical detecting device of the present invention.

US Patent:

20070173787, Jul 26, 2007

Filed:

Nov 1, 2005

Appl. No.:

11/264582

Inventors:

Mark Huang - Pleasanton CA, US
Scott McHugo - Menlo Park CA, US
Anurag Mairal - Newark CA, US
Zara Sieh - Pleasanton CA, US

International Classification:

A61K 9/22

US Classification:

604891100

Abstract:

Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. The drugs, agents, and/or compounds may also be utilized to treat specific diseases, including vulnerable plaque. Therapeutic agents may also be delivered to the region of a disease site. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. These devices may also comprise thin films that perform a number of functions. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.

US Patent:

20080103462, May 1, 2008

Filed:

Oct 22, 2007

Appl. No.:

11/876175

Inventors:

Stuart Wenzel - San Carlos CA, US
Mariam Maghribi - Fremont CA, US
Mark Huang - Pleasanton CA, US
Zara Sieh - Pleasanton CA, US
Michael V. Williamson - Clayton CA, US

International Classification:

A61M 35/00

US Classification:

604313

Abstract:

In one example, the present invention is directed to wound-healing patche that passively or actively draw fluids from a wound using an internal, integral vacuum source. The patches may also include electrodes and electronics for electrostimulation, and bioactive compounds that promote healing, such as anti-inflammatory agents.

US Patent:

20080103558, May 1, 2008

Filed:

Oct 22, 2007

Appl. No.:

11/876192

Inventors:

Stuart Wenzel - San Carlos CA, US
Zara Sieh - Pleasanton CA, US

International Classification:

A61N 1/36

US Classification:

607 61

Abstract:

The present invention is directed to small, low profile, antenna-transmitter systems that attach to exterior of the body and focus electromagnetic (EM) wave energy onto one or more precise regions inside the body. The antenna-transmitter system may also deliver energy to the surface of the body without focusing. The present invention is further directed to a method of focusing energy, such as electromagnetic radiation, onto a single nerve to effect selective neurostimulation, super- or sub-threshold, using a small, low profile, antenna-transmitter system that attaches to the body exterior and focuses electromagnetic wave energy onto the nerve.

US Patent:

20080312600, Dec 18, 2008

Filed:

Jun 12, 2008

Appl. No.:

12/138115

Inventors:

Peter Krulevitch - Pleasanton CA, US
Lorin P. Olson - Scotts Valley CA, US
Zara Sieh - Pleasanton CA, US
Donna Savage - Rolling Hills Estates CA, US

International Classification:

A61M 5/00

US Classification:

604181

Abstract:

A flexible medical device conduit includes an elongated framework formed from a flexible material (e.g., Nitinol) with a body portion, sharp head, distal end and proximal end. The flexible medical device conduit also includes a flexible tube at least partially jacketing the elongated framework between the distal end and the proximal end. Moreover, the sharp head is disposed at the distal end and is configured for subcutaneous skin insertion and the elongated framework and flexible tube define at least one conduit between the elongated framework and the flexible tube, the conduit having an opening at the distal end.

US Patent:

20090247982, Oct 1, 2009

Filed:

Mar 19, 2009

Appl. No.:

12/407173

Inventors:

Peter Krulevitch - Pleasanton CA, US
Robert Wilk - Sierra Village CA, US
Sean O'Connor - West Chester PA, US
Mingqi Zhao - San Jose CA, US
Zara Sieh - Pleasanton CA, US
Donna Savage - Rolling Hills Estates CA, US

Assignee:

LifeScan Inc. - Milpitas CA

International Classification:

A61M 1/00
H04Q 5/22

US Classification:

604500, 604151, 340 101

Abstract:

A medical device pump with a housing with a compartment for removably receiving a cartridge containing a therapeutic agent, a conduit configured to operatively provide a fluid flow path for therapeutic agent to exit from the cartridge, a user activated delivery button, a trigger mechanism, and a mechanical pump mechanism. The trigger mechanism, user activated delivery button and mechanical pump mechanism of the medical device pump are configured such that the trigger mechanism is activated by a user fully activating the user activated delivery button. Moreover, such full activation generates mechanical power employed by, and sufficient for, the mechanical pump mechanism to pump a predetermined volume of therapeutic agent from the cartridge and through the fluid flow path.