Weining Zhao Robieson

US Patent:

20130317054, Nov 28, 2013

Filed:

Mar 13, 2013

Appl. No.:

13/801276

Inventors:

Jeffrey D. BAKER - Evanston IL, US
Weining Z. Robieson - Hawthorn Woods IL, US

Assignee:

ABBVIE INC. - NORTH CHICAGO IL

International Classification:

C07D 471/08

US Classification:

514294, 546 94

Abstract:

An embodiment relates to a selective agonist of neuronal nicotinic acetylcholine receptor α7 subtype, a pharmaceutically suitable salt, prodrug, or a metabolite thereof, for the prevention and treatment of diseases and conditions that are mediated by nicotinic acetylcholine receptors, and methods of use thereof. Another embodiment is a method of administering a pharmaceutically effective amount of a selective agonist of neuronal nicotinic acetylcholine receptor α7 subtype, or a pharmaceutically suitable salt, prodrug, or a metabolite thereof, to a mammal in need thereof.

US Patent:

20200155578, May 21, 2020

Filed:

Nov 15, 2019

Appl. No.:

16/684874

Inventors:

- North Chicago IL, US
Matthew Rosebraugh - Grayslake IL, US
Feroz Jameel - Gurnee IL, US
Nancy Sever - Northbrook IL, US
Maurizio F. Facheris - Chicago IL, US
Weining Z. Robieson - Hawthorn Woods IL, US
Charles S. Locke - Gurnee IL, US
Sven Stodtmann - Neustadt an der Weinstrasse, DE

Assignee:

AbbVie Inc. - North Chicago IL

International Classification:

A61K 31/661
A61K 9/00
A61P 25/16

Abstract:

The present disclosure relates to compositions of levodopa 4′-monophosphate and carbidopa 4′-monophosphate having a weight by weight ratio of about 20:1 and methods of treating Parkinson's disease and associated conditions by subcutaneous administration of such compositions.