Unchalee Kositprapa

US Patent:

6368625, Apr 9, 2002

Filed:

Aug 11, 1999

Appl. No.:

09/372738

Inventors:

John M. Siebert - Eden Prairie MN
Rajendra K. Khankari - Maple Grove MN
Unchalee Kositprapa - Davie FL
S. Indiran Pather - Plymouth MN

Assignee:

Cima Labs Inc. - Eden Prairie MN

International Classification:

A61K 920

US Classification:

424466, 424464, 424465, 424468, 424490, 514770, 5147723, 514777, 514778, 514781

Abstract:

A dosage form which rapidly disintegrates in the mouth and forms a viscous slurry of either microcapsules or a powder is described. The rapidly disintegrating dosage form is meant for direct oral administration by placing a tablet or capsule in the mouth of a patient. Upon disintegration, a viscosity of the resulting slurry increases so as to form an organoleptically pleasant viscous material which retards the spread of insoluble materials including the drug.