Turgut Durduran

US Patent:

20060063995, Mar 23, 2006

Filed:

Apr 13, 2005

Appl. No.:

11/106390

Inventors:

Arjun Yodh - Merion PA, US
Joel Greenberg - Wayne PA, US
Guoqiang Yu - Flemington NJ, US
John Detre - Wynnewood PA, US
Turgut Durduran - Upper Darby PA, US
Mark Burnett - Philadelphia PA, US
Emile Mohler - Radnor PA, US
Harry Quon - Rose Valley PA, US
Stephen Hahn - Glen Mills PA, US

Assignee:

Trustees of the University of Pennsylvania - Philadelphia PA

International Classification:

A61B 5/00
A61B 5/02

US Classification:

600323000, 600504000

Abstract:

An embodiment of the invention includes a device, system and method for determining the characteristics of deep tissue. The novel method includes measuring blood flow rate and oxygenation characteristics of the tissue, and determining oxygen metabolism of the tissue as a function of the measure blood flow rate and measure oxygenation. The blow flow rate characteristics are measured as a function of light fluctuations caused by the tissue, while the oxygenation characteristics are measured as a function of transmission of light through the tissue with respect to the wavelength of light. The tissue may be layered tissue, for example, a portion of a brain. The tissue characteristics may be measured during times of varying levels of exercise intensity.