Bing Wang - Cupertino CA, US Yong-Kang Zhang - San Jose CA, US Jian Chen - Sunnyvale CA, US Wei Zhang - Santa Clara CA, US Jiangao Song - Cupertino CA, US Ughetta Del Balzo - Morgan Hill CA, US Lesley Brown - Reno NV, US Sekhar Boddupalli - San Jose CA, US Steven Bobzin - San Jose CA, US Sylvain Gilat - San Francisco CA, US Guy Miller - San Jose CA, US
Assignee:
Johnson & Johnson Consumer Companies, Inc. - Skillman NJ
International Classification:
A61K 31/415 A01N 43/56
US Classification:
514407, 514406, 514403
Abstract:
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
Cytoprotective Compounds, Pharmaceutical And Cosmetic Formulations, And Methods
Bing Wang - Cupertino CA, US Yong-Kang Zhang - San Jose CA, US Jian Chen - Sunnyvale CA, US Wei Zhang - Santa Clara CA, US Jiangao Song - Cupertino CA, US Ughetta Del Balzo - Morgan Hill CA, US Lesley Brown - East Palo Alto CA, US Sekhar Boddupalli - San Jose CA, US Steven Bobzin - San Jose CA, US Sylvain Gilat - San Francisco CA, US Guy Miller - San Jose CA, US
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
Identifying Therapeutic Compounds Based On Their Physical-Chemical Properties
Sylvain Gilat - San Francisco CA, US Gary Binyamin - Palo Alto CA, US Guy Miller - San Jose CA, US
International Classification:
A61K049/00
US Classification:
424/009200
Abstract:
The present invention is directed to rapid and efficient methods of identifying therapeutic compounds by allowing only the most favorable molecules initially selected based on their physical-chemical profile falling within a range predefined by the physical-chemical/biological relationship of a previously tested small subset of compounds of same core structure to be assayed; and to the therapeutic compositions identified by said methods.
Cytoprotective Compounds, Pharmaceutical And Cosmetic Formulations, And Methods
Bing Wang - Cupertino CA, US Yong-Kang Zhang - San Jose CA, US Jian Chen - Sunnyvale CA, US Wei Zhang - Santa Clara CA, US Jiangao Song - Cupertino CA, US Ughetta Del Balzo - Morgan Hill CA, US Lesley Brown - Reno NV, US Sekhar Boddupalli - San Jose CA, US Steven Bobzin - Malibu CA, US Sylvain Gilat - San Francisco CA, US Guy Miller - San Jose CA, US
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
Cytoprotective Compounds, Pharmaceutical And Cosmetic Formulations, And Methods
Bing Wang - Cupertino CA, US Yong-Kang Zhang - San Jose CA, US Jian Chen - Sunnyvale CA, US Wei Zhang - Santa Clara CA, US Jiangao Song - Cupertino CA, US Ughetta Balzo - Morgan Hill CA, US Lesley Brown - East Palo Alto CA, US Sekhar Boddupalli - San Jose CA, US Steven Bobzin - San Jose CA, US Sylvain Gilat - San Francisco CA, US Guy Miller - San Jose CA, US
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
Youtube
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