Sumit Paliwal from Irvine, CA, age 43

Us Patents

Apparatus For Solubilizing Tissue
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US Patent:

8609041, Dec 17, 2013
Filed:

Apr 27, 2011
Appl. No.:

13/095771
Inventors:

Samir Mitragotri - Santa Barbara CA, US
Sumit Paliwal - Goleta CA, US
Makoto Ogura - Ryugasaki, JP
Russell M. Lebovitz - San Diego CA, US
MyPhuong Lam - Houston TX, US
International Classification:

A61B 10/00
US Classification:

422536, 422 63, 422 64, 422 65, 422 66, 422 67, 436180
Abstract:

Tissue solubilizing apparatuses are provided. The apparatuses may be useful to solubilize tissue, including skin, mucosal membrane, and other tissue. The apparatuses may be further useful to preserve and recover analytes contained within the solubilized skin, mucosal membrane, and other tissue.

Methods Of Tissue-Based Diagnosis
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US Patent:

20100261176, Oct 14, 2010
Filed:

Aug 6, 2008
Appl. No.:

12/664994
Inventors:

Samir M. Mitragotri - Santa Barbara CA, US
Sumit Paliwal - Goleta CA, US
Makoto Ogura - Goleta CA, US
International Classification:

C12Q 1/68
C12Q 1/02
G01N 33/53
C12Q 1/60
C12Q 1/04
US Classification:

435 6, 435 29, 435 71, 435 11, 435 34
Abstract:

The current invention provides methods, as well as compositions useful in such methods, involving application of energy to a tissue of interest to generate a liquefied sample comprising tissue constituents so as to provide for rapid tissue sampling, as well as qualitative and/or quantitative detection of analytes that may be part of tissue constituents (e.g., several types of biomolecules, drugs, and microbes). Determination of tissue composition can be used in a variety of applications, including diagnosis or prognosis of local as well as systemic diseases, evaluating bioavailability of therapeutics in different tissues following drug administration, forensic detection of drugs-of-abuse, evaluating changes in the tissue microenvironment following exposure to a harmful agent, and various other applications.

System, Method And Device For Tissue-Based Diagnosis
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US Patent:

20110212485, Sep 1, 2011
Filed:

Feb 12, 2010
Appl. No.:

13/126105
Inventors:

Samir Mitragotri - Santa Barbara CA, US
Sumit Paliwal - Goleta CA, US
Markoto Ogura - Ryugasaki, JP
Assignee:

The Regents of the University of California - Oakland CA
International Classification:

C12Q 1/02
C12M 1/00
C12M 1/34
C12M 1/42
C12N 5/07
A61B 1/00
US Classification:

435 29, 4352831, 4352871, 4352887, 435325, 600104
Abstract:

The current invention provides devices, methods and systems involving application of energy and/or a liquefaction promoting medium to a tissue of interest to generate a liquefied sample comprising tissue constituents so as to provide for rapid tissue sampling, tissue decontamination as well as qualitative and/or quantitative detection of analytes that may be part of tissue constituents (e.g., several types of biomolecules, drugs, and microbes). In addition, the current invention provides specific compositions of the said liquefaction promoting medium so as to facilitate liquefaction, preserve liquefied tissue constituents, and enable delivery of molecules into tissues. Determination of tissue composition in the liquefied tissue sample can be used in a variety of applications, including diagnosis or prognosis of local as well as systemic diseases, evaluating bioavailability of therapeutics in different tissues following drug administration, forensic detection of drugs-of-abuse, evaluating changes in the tissue microenvironment following exposure to a harmful agent, and various other applications. The methods, devices and systems are used to deliver one or more drugs through or into the site of the tissue to be liquefied.

Stable Hydrogel Compositions Including Additives
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US Patent:

20120208890, Aug 16, 2012
Filed:

Jan 13, 2012
Appl. No.:

13/350518
Inventors:

Cecile Gousse - Dingy Saint Clair`, FR
Pierre F. Lebreton - Annecy, FR
Nicolas Prost - Mornant, FR
Sumit Paliwal - Goleta CA, US
Dennis Van Epps - Goleta CA, US
Assignee:

ALLERGAN, INC. - Irvine CA
International Classification:

A61K 8/41
A61Q 19/08
A61K 8/42
US Classification:

514626, 514653
Abstract:

The present specification generally relates to hydrogel compositions and methods of treating a soft tissue condition using such hydrogel compositions.

Composition For Solubilizing Tissue Comprising 3-(Decyl Dimethyl Ammonio) Propane Sulfonate And Tetraethylene Glycol Dodecyl Ether
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US Patent:

8389582, Mar 5, 2013
Filed:

Apr 27, 2011
Appl. No.:

13/095639
Inventors:

Samir Mitragotri - Santa Barbara CA, US
Sumit Paliwal - Goleta CA, US
Makoto Ogura - Ryugasaki, JP
Russell M. Lebovitz - San Diego CA, US
International Classification:

A01N 31/14
A01N 33/12
A61N 1/30
A61B 10/00
US Classification:

514723, 514642, 600562, 604 20
Abstract:

Tissue solubilizing compositions are provided. The compositions comprise 3-(decyl dimethyl ammonio) propane sulfonate and polyethylene glycol dodecyl ether, such as tetraethylene glycol dodecyl ether. The compositions may be useful to solubilize tissue, including skin, mucosal membrane, and other tissue. The compositions may be further useful to preserve and recover analytes contained within the solubilized skin, mucosal membrane, and other tissue.

Dermal Filler Compositions For Fine Line Treatment
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US Patent:

20200353124, Nov 12, 2020
Filed:

Jul 24, 2020
Appl. No.:

16/938504
Inventors:

- Pringy, FR
Xiaojie YU - Irvine CA, US
Futian LIU - Sunnyvale CA, US
Sumit PALIWAL - Goleta CA, US
Nicholas J. MANESIS - Escondido CA, US
International Classification:

A61L 27/20
A61K 8/73
A61Q 19/08
A61K 8/33
A61L 27/54
Abstract:

The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.

Dermal Filler Compositions For Fine Line Treatment
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US Patent:

20180193523, Jul 12, 2018
Filed:

Mar 7, 2018
Appl. No.:

15/914274
Inventors:

- Irvine CA, US
Xiaojie Yu - Irvine CA, US
Futian Liu - Sunnyvale CA, US
Sumit Paliwal - Goleta CA, US
Nicholas J. Manesis - Escondido CA, US
International Classification:

A61L 27/20
A61K 8/73
A61K 8/33
A61L 27/54
A61Q 19/08
Abstract:

The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.

Stable Hydrogel Compositions Including Additives
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US Patent:

20170216488, Aug 3, 2017
Filed:

Apr 14, 2017
Appl. No.:

15/487767
Inventors:

Pierre F. Lebreton - Annecy, FR
Nicolas Prost - Mornant, FR
Sumit Paliwal - Grapevine TX, US
Dennis Van Epps - Goleta CA, US
International Classification:

A61L 27/20
A61K 31/167
A61K 31/4174
A61K 31/137
A61L 27/54
A61L 27/52
Abstract:

Dermal filler hydrogel compositions, methods of making them, and methods of using them to treat soft tissue conditions, such as wrinkles, are provided. The compositions contain a crosslinked hyaluronic acid-based polymer and one or more additional ingredients, and are stable to sterilization by heat and/or pressure treatment. The additional ingredients include vasoconstrictive agents, antioxidant agents, such as a ascorbic acid agents, and/or anesthetic agents.