Sita G Awasthi from 124 Tall Trees Dr, Cynwyd, PA 19004, age 60, Phone: 6107470604

Herpes Simplex Virus Combined Subunit Vaccines And Methods Of Use Thereof
view source
US Patent:

20090148467, Jun 11, 2009
Filed:

Jul 24, 2008
Appl. No.:

12/179439
Inventors:

Harvey Friedman - Merion PA, US
Sita Awasthi - Bala Cynwyd PA, US
John Lubinski - Malvern PA, US
International Classification:

A61K 39/245
A61K 39/12
US Classification:

4241861, 4242311
Abstract:

This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV thereby vaccinating a subject against HSV and treating, suppressing, inhibiting, and/or reducing an incidence of an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.

Herpes Simplex Virus Combined Subunit Vaccines And Methods Of Use Thereof
view source
US Patent:

20110256176, Oct 20, 2011
Filed:

Nov 13, 2008
Appl. No.:

12/270772
Inventors:

Harvey FRIEDMAN - Merion PA, US
Sita AWASTHI - Bala Cynwyd PA, US
John LUBINSKI - Malvern PA, US
International Classification:

A61K 39/245
A61P 31/22
A61P 37/04
US Classification:

4242311
Abstract:

This invention provides vaccines comprising two or more recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV thereby vaccinating a subject against HSV and treating, suppressing, inhibiting, and/or reducing an incidence of an an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.

Herpes Simplex Virus Combined Subunit Vaccines And Methods Of Use Thereof
view source
US Patent:

20130028925, Jan 31, 2013
Filed:

Jun 4, 2012
Appl. No.:

13/487966
Inventors:

Harvey FRIEDMAN - Merion PA, US
Sita Awasthi - Bala Cynwyd PA, US
John Lubinski - Malvern PA, US
International Classification:

A61K 39/245
A61P 31/22
US Classification:

4241861
Abstract:

This invention provides immunogenic compositions comprising two or three recombinant Herpes Simplex Virus (HSV) proteins selected from a gD protein, a gC protein and a gE protein; and methods of impeding immune evasion by HSV, inducing an anti-HSV immune response, and treating, suppressing, inhibiting, and/or reducing an incidence of an HSV infection or a symptom or manifestation thereof, comprising administration of a vaccine of the present invention.

Modified Mrna Vaccines Encoding Herpes Simplex Virus Glycoproteins And Uses Thereof
view source
US Patent:

20210386853, Dec 16, 2021
Filed:

Jun 17, 2021
Appl. No.:

17/349929
Inventors:

- Philadelphia PA, US
Drew WEISSMAN - Wynnewood PA, US
Sita AWASTHI - Bala Cynwyd PA, US
Gary Cohen - Havertown PA, US
Assignee:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:

A61K 39/245
A61P 31/22
A61K 9/00
C07K 14/005
C12N 7/00
C12N 15/11
Abstract:

The present invention provides compositions for the prevention and treatment of genital herpes, comprising nucleoside modified mRNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.

Modified Mrna Vaccines Encoding Herpes Simplex Virus Glycoproteins And Uses Thereof
view source
US Patent:

20200276300, Sep 3, 2020
Filed:

Aug 17, 2018
Appl. No.:

16/640008
Inventors:

- Philadelphia PA, US
Drew WEISSMAN - Wynnewood PA, US
Sita AWASTHI - Bala Cynwyd PA, US
Gary Cohen - Havertown PA, US
Assignee:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:

A61K 39/245
C07K 14/005
C12N 7/00
C12N 15/11
A61K 9/00
A61P 31/22
Abstract:

The present invention provides compositions for the prevention and treatment of genital herpes, comprising nucleoside modified m RNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.