Baha M. Alak - Beaverton OR Richard L. Stouffer - Aloha OR Don P. Wolf - Portland OR Teresa K. Woodruff - San Francisco CA
Assignee:
Genentech, Inc. - South San Francisco CA Oregon Regional Primate Research Center - Beaverton OR
International Classification:
C12N 500
US Classification:
435366
Abstract:
A method is provided for increasing the fertilization potential of oocytes comprising culturing oocytes in vitro with an effective amount of inhibin, activin, or a combination of inhibin and activin. Preferably the oocytes being cultured are immature. After the culturing step, the oocytes can be fertilized. The oocytes are suitably cryopreserved and thawed before the culturing step.
Use Of Human Inhibin And Human Activin To Increase The Number Of Mature Primate Oocytes
A method is provided for increasing the fertilization potential of oocytes comprising culturing oocytes in vitro with an effective amount of inhibin, activin, or a combination of inhibin and activin. Preferably the oocytes being cultured are immature. After the culturing step, the oocytes can be fertilized. The oocytes are suitably cryopreserved and thawed before the culturing step.
Resumes
Senior Scientist And Division Head At Oregon Health & Science University, Oregon National Primate Research Center