Arno VILLRINGER - Berlin, DE Daniel MARGULIES - Berlin, DE Yating LV - Leipzig, DE Richard Cameron CRADDOCK - Hoboken NJ, US
International Classification:
A61B 5/055
US Classification:
600410
Abstract:
A method and apparatus for visualization of tissue areas insufficiently supplied with blood, in particular in the event of an acute stroke, by evaluation of local fluctuations of a BOLD signal produced and recorded by an apparatus; passed to a data detection device; pre-processed in a first evaluation device for image recognition; subjected to a time delay analysis applied to the BOLD signal data of at least one voxel in a second evaluation device in order to calculate a time dependent positive and negative phase shift of the BOLD signal data; and assigned a reference value which is an estimated time delay between the BOLD signal data of at least one voxel and the entire average time course of a selected region during the recording of the BOLD data in order to estimate modified BOLD signal data which are used to determine at least one area of the hypoperfused tissue.
Gale Washburn, Roberta Morgan, Laquita Carroll, Lee Vogt, Brandon Stoup, Terry Wade, Cindy Murray, Diane Grove, Debbie Matthews, Kerman Raines, Randy Mcfarland