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Richard J Bram

age ~66

from Rochester, MN

Also known as:
  • Richard Jerome Bram
  • Rick J Bram
  • Dick J Bram
Phone and address:
5024 Nicklaus Dr NW, Rochester, MN 55901
5072506919

Richard Bram Phones & Addresses

  • 5024 Nicklaus Dr NW, Rochester, MN 55901 • 5072506919
  • 857 Harbor Isle Cir E, Memphis, TN 38103
  • 114 Burbank Ave, San Mateo, CA 94403
  • Menlo Park, CA
  • 1432 James Ave, Redwood City, CA 94062
  • Minneapolis, MN
  • Mountain View, CA

Work

  • Company:
    Mayo Clinic
  • Address:
    200 1St St Sw, Rochester, MN 55905
  • Phones:
    5072842511

Education

  • School / High School:
    Stanford University School Of Medicine
    1987

Languages

English

Awards

Healthgrades Honor Roll

Ranks

  • Certificate:
    Pediatric Oncology & Pediatric Hematology, 2002

Specialities

Oncology • Pediatric Hematology & Oncology
Name / Title
Company / Classification
Phones & Addresses
Richard Jerome Bram
Richard Bram MD,PHD
Pediatric Oncologist · Internist
200 1 St SW, Rochester, MN 55905
8006604582

Us Patents

  • Antibodies To A Lymphocyte Surface Receptor That Binds Caml And Methods Of Use Thereof

    view source
  • US Patent:
    6500428, Dec 31, 2002
  • Filed:
    Feb 14, 2001
  • Appl. No.:
    09/782857
  • Inventors:
    Richard J. Bram - Memphis TN
    Gotz Von Bulow - Memphis TN
  • Assignee:
    St. Jude Childrens Research Hospital - Memphis TN
  • International Classification:
    C07K 1600
  • US Classification:
    4241331, 5303893, 5303873, 5303879, 5303887, 5303891, 53038822, 4241531, 4241441
  • Abstract:
    A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, are shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e. g. , during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions).
  • Lymphocyte Surface Receptor That Binds Caml And Methods Of Use Thereof

    view source
  • US Patent:
    7355005, Apr 8, 2008
  • Filed:
    Dec 23, 2005
  • Appl. No.:
    11/318156
  • Inventors:
    Richard J. Bram - Rochester MN, US
    Gotz Von Bulow - Carmel IN, US
  • Assignee:
    St. Jude Children's Research Hospital - Memphis TN
  • International Classification:
    C07K 14/435
    A61K 38/17
  • US Classification:
    530350, 530300, 514 12
  • Abstract:
    A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, is shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e. g. , during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions).
  • Lymphocyte Surface Receptor That Binds Caml And Methods Of Use Thereof

    view source
  • US Patent:
    20030082173, May 1, 2003
  • Filed:
    Nov 12, 2002
  • Appl. No.:
    10/293816
  • Inventors:
    Richard Bram - Memphis TN, US
    Gotz Bulow - Memphis TN, US
  • Assignee:
    St. Jude Children's Research Hospital, Inc.
  • International Classification:
    G01N033/567
    A61K039/395
  • US Classification:
    424/133100, 435/007210
  • Abstract:
    A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, are shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e.g., during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions).
  • Lymphocyte Surface Receptor That Binds Caml And Methods Of Use Thereof

    view source
  • US Patent:
    20050183148, Aug 18, 2005
  • Filed:
    Mar 14, 2005
  • Appl. No.:
    11/079418
  • Inventors:
    Richard Bram - Rochester MN, US
    Gotz Von Bulow - Carmel IN, US
  • Assignee:
    St. Jude Children's Research Hospital - Memphis TN
  • International Classification:
    A01K067/027
    C12N005/06
  • US Classification:
    800018000, 435354000
  • Abstract:
    A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, is shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e.g., during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions).
  • Lymphocyte Surface Receptor That Binds Caml And Methods Of Use Thereof

    view source
  • US Patent:
    20090226473, Sep 10, 2009
  • Filed:
    Feb 7, 2008
  • Appl. No.:
    12/027720
  • Inventors:
    Richard J. Bram - Rochester MN, US
    Gotz Von Bulow - Carmel IN, US
  • Assignee:
    St. Jude Children's Research Hospital - Memphis TN
  • International Classification:
    A61K 39/00
    A61P 35/00
  • US Classification:
    4241851
  • Abstract:
    A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, is shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e.g., during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions).
  • Lymphocyte Surface Receptor That Binds Caml, Nucleic Acids Encoding The Same And Methods Of Use Thereof

    view source
  • US Patent:
    59691026, Oct 19, 1999
  • Filed:
    Mar 3, 1997
  • Appl. No.:
    8/810572
  • Inventors:
    Richard J. Bram - Memphis TN
    Gotz Von Bulow - Memphis TN
  • Assignee:
    St. Jude Children's Research Hospital - Memphis TN
  • International Classification:
    C07K 14705
  • US Classification:
    530350
  • Abstract:
    A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, are shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e. g. , during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions).
  • Dna Encoding Calcium-Signal Modulating Cyclophilin Ligand

    view source
  • US Patent:
    55232272, Jun 4, 1996
  • Filed:
    Jun 17, 1994
  • Appl. No.:
    8/261662
  • Inventors:
    Richard J. Bram - Memphis TN
    Gerald R. Crabtree - Woodside CA
  • Assignee:
    The Board of Trustees of the Leland Stanford Junior Univ. - Stanford CA
  • International Classification:
    C12N 508
    C12N 1512
  • US Classification:
    4352402
  • Abstract:
    DNA and protein compositions are provided for calcium-signal modulating cyclophilin ligand which are shown to act in the calcium-dependent pathway for activation of a number of genes. The DNA composition and proteins may be used in investigating the processes associated with calcium-dependent activation of genes, as well as screening of drugs for interaction with the subject proteins for modulating cell processes, e. g. T-cell activation.
  • Nucleic Acids Encoding A Lymphocyte Surface Receptor That Binds Caml

    view source
  • US Patent:
    63162229, Nov 13, 2001
  • Filed:
    Apr 12, 1999
  • Appl. No.:
    9/290333
  • Inventors:
    Richard J. Bram - Memphis TN
    Gotz Von Bulow - Memphis TN
  • Assignee:
    St. Jude Children's Research Hospital - Memphis TN
  • International Classification:
    C12N 1500
    C12N 1563
    C12N 500
    C07H 2102
    C07H 2104
  • US Classification:
    435 691
  • Abstract:
    A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, are shown to increase lymphocyte response, and to identify ligands of the protein receptor. Antibodies to the proteins of the invention are generated for diagnostic therapeutics. The protein and DNA can also be used for diagnostic purposes and for identifying agents for modulating the calcium induced activation pathway. A particular advantage of the present invention is that it provides lymphocyte activation of receptor found on all B cells, but only on a subset of T cells. The receptor can thus be targeted to specifically regulate B cell responses without affecting mature T cell activity. Such targeting specificity is always advantageous, particularly where an increase or decrease of antibody production is desired, e. g. , during an infection (increase) or to avoid immune complex deposition complications (rheumatoid arthritis, glomerulonephritis, and other auto immune conditions).

Resumes

Richard Bram Photo 1

Chair

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Location:
Rochester, MN
Work:
Mayo Clinic
Chair
Richard Bram Photo 2

Richard Bram

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Wikipedia References

Richard Bram Photo 3

Richard Bram

Medicine Doctors

Richard Bram Photo 4

Dr. Richard J Bram, Rochester MN - MD (Doctor of Medicine)

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Specialties:
Oncology
Pediatric Hematology & Oncology
Address:
Mayo Clinic
200 1St St Sw, Rochester, MN 55905
5072842511 (Phone)
Certifications:
Pediatric Oncology & Pediatric Hematology, 2002
Pediatrics, 1993
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Stanford University School Of Medicine
Graduated: 1987
Medical School
Stanford University Hospital
Graduated: 1987
Richard Bram Photo 5

Richard J. Bram

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Specialties:
Internal Medicine
Work:
Mayo ClinicMayo Clinic Pediatric Hematology/Oncology
200 1 St Sw Mayo 16, Rochester, MN 55905
5072842695 (phone), 5072840727 (fax)
Education:
Medical School
Stanford University School of Medicine
Graduated: 1987
Conditions:
Anemia
Hemolytic Anemia
Hemophilia A or B
Iron Deficiency Anemia
Leukemia
Languages:
English
Description:
Dr. Bram graduated from the Stanford University School of Medicine in 1987. He works in Rochester, MN and specializes in Internal Medicine. Dr. Bram is affiliated with Saint Marys Hospital.
Richard Bram Photo 6

Richard J Bram, Rochester MN

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Specialties:
Pediatric Hematologist / Oncologist
Address:
200 1St St Sw, Rochester, MN 55905
Education:
Stanford University, School of Medicine - Doctor of Medicine
Board certifications:
American Board of Pediatrics Sub-certificate in Pediatric Hematology/Oncology (Pediatrics)

Youtube

Making of "Bram Stoker's Dracula" (2/3)

[deutsch untertitelt]

  • Category:
    Film & Animation
  • Uploaded:
    28 Feb, 2010
  • Duration:
    9m 26s

Bram Stoker's Dracula (1992) Teaser Trailer

Original teaser trailer for the 1992 film Bram Stoker's Dracula. Starr...

  • Category:
    Film & Animation
  • Uploaded:
    28 Oct, 2009
  • Duration:
    1m 31s

Dracula Imagination Theater Placerville

Dracula Show trailer. Playing at the Imagination Theater located in Pl...

  • Category:
    Entertainment
  • Uploaded:
    15 Oct, 2010
  • Duration:
    1m 42s

"Bram Stokers Dracula" Making Of (In Spanish)...

A NEW "MAKING OF" OR BIOGRAPHY EVERY WEEK!!!. UN NUEVO "MAKING OF" O B...

  • Category:
    Entertainment
  • Uploaded:
    11 Mar, 2011
  • Duration:
    10m 2s

Bram Stoker's Dracula - Official Trailer [HD]

Release Date: November 13, 1992 Gary Oldman, Winona Ryder and Anthony ...

  • Category:
    Film & Animation
  • Uploaded:
    17 Nov, 2011
  • Duration:
    2m 39s

Vladislaus Dracula - Love Remembered

This is a different sort of tribute to one of my most loved vampire ch...

  • Category:
    Film & Animation
  • Uploaded:
    20 Nov, 2008
  • Duration:
    4m 12s

Richard Levi record breaking 117 not out | Ne...

24 year old Richard Levi smashed 117 not out off just 51 balls against...

  • Category:
    Sports
  • Uploaded:
    20 Feb, 2012
  • Duration:
    2m 55s

"Bram Stokers Dracula" Making Of (In Spanish)...

A NEW "MAKING OF" OR BIOGRAPHY EVERY WEEK!!!. UN NUEVO "MAKING OF" O B...

  • Category:
    Entertainment
  • Uploaded:
    11 Mar, 2011
  • Duration:
    15m 1s

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