The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
Hassan Serhan - S. Easton MA, US Michael Slivka - Taunton MA, US Ramon Ruberte - Ann Arbor MI, US Michael O'Neil - West Barnstable MA, US Rehan Khanzada - Middleboro MA, US
Assignee:
DePuy Spine, Inc. - Raynham MA
International Classification:
A61F 2/30
US Classification:
606071000
Abstract:
Various exemplary methods and devices are provided for fixing an implant to native tissue, such as, bone. The devices can include a body having an upper surface, a lower tissue contacting surface, and an implant receiving opening extending therebetween. The body can further include first and second portions each having an implant contacting surface and a hinge for connecting the first and second portions. In use, the hinge can allow pivotal movement between the first and second portions such that an implant can be fixed therebetween.
Robert Fraser - Myrtle Bank, AU Rehan Khanzada - Middleboro MA, US Michael O'Neil - West Barnstable MA, US
Assignee:
DePuy Spine, Inc. - Raynham MA
International Classification:
A61B 17/80 A61B 17/84
US Classification:
606071000, 606072000, 606070000
Abstract:
Various exemplary methods and devices are provided for fixing an implant to native tissue, such as, bone. The devices can include first and second plate bodies, each having an upper surface and a lower tissue contacting surface. The bodies can provides a large contact area for fixing the tissue implant to bone, such that the implant can be securely held in position without requiring penetration of the implant. In one embodiment, the plate bodies can include at least one aperture for receiving a fixation device and a tissue implant receiving opening through which a tissue implant can be threaded prior to fixing the plate bodies to bone.
Venkata R. Garigapati - Southborough MA, US Dongling Su - Franklin MA, US Rehan Khanzada - Middleborough MA, US Steven J. Sawamura - Newark CA, US
International Classification:
A61K 38/00 A61P 19/08 A61L 17/00
US Classification:
606 92, 514 2
Abstract:
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
Novel Carriers For Coating Growth Factors Onto Sutures
Dongling Su - Franklin MA, US Rehan Khanzada - Middleborough MA, US Steven J. Sawamura - Newark CA, US
Assignee:
DEPUY SYNTHES PRODUCTS, LLC - Raynham MA
International Classification:
A61K 38/18
US Classification:
514 88, 530399
Abstract:
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
Provided are compositions for wound treatment comprising foam impregnated with honey, methods of making such compositions, and methods of treating wounds with such compositions.
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
Aug 2011 to 2000 Senior Systems Engineer - RequirementsAdvanced Technologies and Regenerative Medicine (ATRM), a Johnson & Johnson Company Somerville, NJ Oct 2008 to Aug 2011 Senior Engineer, Research and DevelopmentJohnson & Johnson Regenerative Therapeutics Raynham, MA Jan 2006 to Oct 2008 Senior Process Development Engineer, Process DevelopmentBone Technology Raynham, MA Apr 2005 to Dec 2005 Engineer IIDePuy Spine, a Johnson & Johnson Company Raynham, MA Mar 2001 to Apr 2005 Manufacturing Engineer II, OperationsStryker Allendale, NJ May 2000 to Sep 2000 Custom Knee Instrument Team InternBecton Dickinson Franklin Lakes, NJ Sep 1999 to Jan 2000 Safety Leadership Co-op
Education:
University of Massachusetts Dartmouth, Charlton College of Business North Dartmouth, MA Dec 2007 MBANew Jersey Institute of Technology (NJIT), Newark College of Engineering Newark, NJ Dec 2000 BS in Biomedical EngineeringRutgers University, Cook College New Brunswick, NJ May 1996 BS in Biological Sciences
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