Pearl Shwe Cho Tay

US Patent:

20180028537, Feb 1, 2018

Filed:

Mar 17, 2017

Appl. No.:

15/462444

Inventors:

- Sunnyvale CA, US
Ching Wah Chong - Fremont CA, US
Robert Kuehl - San Francisco CA, US
Cassandra Shu - Belmont CA, US
Pearl Shwe-Cho Tay - Union City CA, US
James Francis Hulvat - Bend OR, US
Alexander Jacob McVey - Bend OR, US
Ryan Mitchell Minikis - Bend OR, US

International Classification:

A61K 31/519
A61K 47/26
A61K 47/02
A61K 9/10
A61K 9/20
A61K 9/16
A61K 47/38
A61K 47/12

Abstract:

Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including novel pharmaceutical formulations thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

US Patent:

20170079981, Mar 23, 2017

Filed:

Dec 6, 2016

Appl. No.:

15/370535

Inventors:

- Sunnyvale CA, US
Ching Wah Chong - Fremont CA, US
Robert Kuehl - San Francisco CA, US
Cassandra Shu - Belmont CA, US
Pearl Shwe-Cho Tay - Union City CA, US
James F. Hulvat - Bend OR, US
Alexander J. McVey - Bend OR, US
Ryan M. Minikis - Bend OR, US

International Classification:

A61K 31/519
A61K 9/10
A61K 47/26
A61K 47/38
A61K 47/02
A61K 47/12

Abstract:

Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including novel pharmaceutical formulations thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

US Patent:

20160038496, Feb 11, 2016

Filed:

Aug 7, 2015

Appl. No.:

14/821290

Inventors:

- Sunnyvale CA, US
Harisha ATLURI - Palo Alto CA, US
Robert KUEHL - San Francisco CA, US
Pearl Shwe-Cho TAY - Union City CA, US
Ryan Mitchell MINIKIS - Bend OR, US
James Francis HULVAT - Bend OR, US
Alexander Jacob MCVEY - Bend OR, US

International Classification:

A61K 31/519
A61K 47/02
A61K 47/38
A61K 47/12
A61K 9/10
A61K 47/26

Abstract:

Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including novel pharmaceutical formulations thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.