Bob Sherwood - Amenia NY, US Joseph Zeleznik - Poughkeepsie NY, US Michael Mallon - New Fairfield CT, US
Assignee:
JRS Pharma LP - Patterson NY
International Classification:
A61K007/42 A61K007/021
US Classification:
424/059000, 424/063000, 106/205900
Abstract:
A composition has a particulate agglomerate of microcrystalline cellulose co-processed with additive materials, such as silicon dioxide, that are in intimate association with each other, the additive materials being integrated with or at least partially coating the microcrystalline cellulose. The additive materials are present in an amount of about 1% to about 99% by weight, based on the weight of the microcrystalline cellulose. When the material is silicon dioxide, the silicon dioxide is present in an amount of about 21% to about 99% by weight. A method of preparing a composition includes forming an aqueous slurry containing a mixture of microcrystalline cellulose in the form of a wet cake and additive materials; and drying the slurry to obtain a composition comprising a plurality of agglomerated particles of microcrystalline cellulose in intimate association with the additive material. In another embodiment, the composition has a particulate agglomerate of pure additive material, such as silicon dioxide.
John J. Niedospial - Princeton Juntion NJ Linn C. Hoover - Webster NY Michael T. Mallon - New Fairfield CT James E. Hoyes - Somerset NJ Robert J. DeLuccia - Mamaroneck NY
Assignee:
Sanofi Winthrop, Inc. - New York NY
International Classification:
A61M 500
US Classification:
604283
Abstract:
A coupling system for transferring fluids from a medicament-containing cartridge to an injection site comprises a fluid flow channel, a blunt cannula defining the distal end of the fluid flow channel, a needle cannula defining the proximal end of the fluid flow channel, and means for fixedly connecting the needle cannula to the blunt cannula.
John J. Niedospial - Princeton Junction NJ Linn C. Hoover - Webster NY Michael T. Mallon - New Fairfield CT James E. Hoyes - Somerset NJ
Assignee:
Sanofi Winthrop, Inc. - Malvern PA
International Classification:
A61M 500
US Classification:
604283
Abstract:
A coupling system for transferring fluids from a medicament-containing cartridge to an injection site comprises a fluid flow channel, a blunt cannula defining the distal end of the fluid flow channel, a needle cannula defining the proximal end of the fluid flow channel, and means for fixedly connecting the needle cannula to the blunt cannula.