Matthew Robert Lewin

US Patent:

6931433, Aug 16, 2005

Filed:

Jan 31, 2001

Appl. No.:

09/774870

Inventors:

Geoffrey D. Ralston - Menlo Park CA, US
David H. Nakayama - Palo Alto CA, US
Matthew E. Lewin - Santa Clara CA, US
Ravichandran Menon Jayachandran - Sunnyvale CA, US
Brian R. Woods - San Francisco CA, US
Udi Manber - Palo Alto CA, US

Assignee:

Yahoo! Inc. - Santa Clara CA

International Classification:

H06F015/16

US Classification:

709206, 709207

Abstract:

The invention relates to processing of electronic text communication distributed in bulk. In one embodiment, a method for detecting electronic text communication distributed in bulk is disclosed. After receiving a first electronic text communication, it is processed with an algorithm to produce a first fingerprint. A time period is begun for the first electronic text communication. After receiving a second electronic text communications, it is also processed with the algorithm to produce a second fingerprint. The first fingerprint to the second fingerprint are compared to determine if the first electronic text communication is similar to the second electronic text communication. A count for the first electronic text communication is updated based upon the comparison. It is determined if the count during the time period reaches a first threshold.

US Patent:

7359948, Apr 15, 2008

Filed:

Dec 21, 2004

Appl. No.:

11/019839

Inventors:

Geoffrey D. Ralston - Menlo Park CA, US
David H. Nakayama - Palo Alto CA, US
Matthew E. Lewin - Santa Clara CA, US
Ravichandran Menon Jayachandran - Sunnyvale CA, US
Brian R. Woods - San Francisco CA, US
Udi Manber - Palo Alto CA, US

Assignee:

Yahoo! Inc. - Sunnyvale CA

International Classification:

G06F 15/16

US Classification:

709206, 379 8822

Abstract:

The invention relates to processing similar electronic text communication. In one step, a first electronic and a second electronic submission, that are part of a plurality of electronic submissions, are received. A first portion is extracted from the first electronic submission and a second portion from the second electronic submission. Content of the first electronic submission influences extraction of the first portion and content of the second electronic submission influences extraction of the second portion. Locations for the first and second portions could vary with content. A first code is determined for the first portion and a second code for the second portion, where the first code is indicative of the first portion and the second code is indicative of the second portion. The first code to the second code are compared to associate the first and second electronic submission together.

US Patent:

6842773, Jan 11, 2005

Filed:

Jan 31, 2001

Appl. No.:

09/773250

Inventors:

Geoffrey D. Ralston - Menlo Park CA, US
David H. Nakayama - Palo Alto CA, US
Matthew E. Lewin - Santa Clara CA, US
Ravichandran Menon Jayachandran - Sunnyvale CA, US
Brian R. Woods - San Francisco CA, US
Udi Manber - Palo Alto CA, US

Assignee:

Yahoo ! Inc. - Santa Clara CA

International Classification:

G06F 1516

US Classification:

709206, 709207, 379 8

Abstract:

The invention relates to processing of electronic text communication distributed in bulk. In one embodiment, a process for blocking electronic text communication distributed in bulk is disclosed. In the process, a first electronic and a second electronic submission are received. A first portion is extracted from the first electronic submission and a second portion is extracted from the second electronic submission. A first code is determined for the first portion and a second code is determined for the second portion. The first code is indicative of the first portion and the second code is indicative of the second portion. After the first code is compared to the second code, the second electronic submission is filtered in response to that comparison.

US Patent:

20210260029, Aug 26, 2021

Filed:

Mar 29, 2021

Appl. No.:

17/215466

Inventors:

- Corte Madera CA, US
Matthew R. Lewin - Corte Madera CA, US

International Classification:

A61K 31/404
A61K 9/00
A61K 45/06
A61K 31/245
A61K 31/445
A61K 31/24
A61K 31/167
A61K 31/16
A61K 31/381
A61K 31/405
A61K 31/541
A61K 38/57
A61K 39/395
C07K 16/18

Abstract:

The invention provides methods of treatment, pharmaceutical compositions, systems and kits appropriate for first line and/or adjunct therapy with antivenom using at least one active component, in some instances at least two active components and in other instances no more than two active components selected from the group consisting of a selective secretory PLAinhibitor (sPLA2 or PLAinhibitor), a metalloproteinase inhibitor, a serine protease inhibitor, antivenom, one or more acetylcholinesterase inhibitors or a nAChR agonist paired with a mAChR antagonist, a NMDA receptor antagonist and a spreading factor inhibitor to treat a subject who suffers from an envenomation, preferably at the time of envenomation and often within a period of less than about an hour after an envenomation or 6 hours after an envenomation and throughout the course of treatment at time with or without anti-venom as an adjunct therapy after an envenomation by, for example, a snake or invertebrate.

US Patent:

20210220332, Jul 22, 2021

Filed:

May 1, 2017

Appl. No.:

16/097160

Inventors:

- Corte Madera CA, US
Matthew R. Lewin - Corte Madera CA, US

International Classification:

A61K 31/4045
A61K 31/192
A61K 45/06
A61P 39/02

Abstract:

Provided are methods for treatment of pathological conditions causing hemolysis, cerebral edema, acute kidney injury and non-anaphylactic shock, including envenomation, trauma, cerebral malaria and mast-cell diseases using at least one PLA2 inhibitor, alone or in combination with other agents. The unexpected versatility of PLA2 inhibitors, their dosage forms and combinations make them candidates as essential medicines for the developing world.

US Patent:

20170354642, Dec 14, 2017

Filed:

Nov 20, 2015

Appl. No.:

15/528418

Inventors:

- Corte Madera CA, US
Matthew R. Lewin - Corte Madera CA, US

International Classification:

A61K 31/404
A61K 39/395
A61K 9/00
C07K 16/18
A61K 45/06

Abstract:

The invention provides methods of treatment, pharmaceutical compositions, systems and kits appropriate for first line and/or adjunct therapy with antivenom using at least one active component, in some instances at least two active components and in other instances no more than two active components selected from the group consisting of a selective secretory PLAinhibitor (sPLA2 or PLAinhibitor), a metalloproteinase inhibitor, a serine protease inhibitor, antivenom, one or more acetylcholinesterase inhibitors or a nAChR agonist paired with a mAChR antagonist, a NMDA receptor antagonist and a spreading factor inhibitor to treat a subject who suffers from an envenomation, preferably at the time of envenomation and often within a period of less than about an hour after an envenomation or 6 hours after an envenomation and throughout the course of treatment at time with or without antivenom as an adjunct therapy after an envenomation by, for example, a snake or invertebrate.

US Patent:

20150224094, Aug 13, 2015

Filed:

Sep 6, 2013

Appl. No.:

14/427035

Inventors:

Matthew R. LEWIN - , US
Matthew R. Lewin - Corte Madera CA, US

Assignee:

OPHIREX, INC. - Corte Madera CA

International Classification:

A61K 31/4425
A61K 9/00
A61K 31/40

Abstract:

Methods and kits for treating or reducing the likelihood of neurotoxin-induced respiratory failure in a subject, such as a victim of neurotoxic envenomation are provided. Also provided are methods for treating or reducing the likelihood of residual neuromuscular blockade in a subject to whom a nondepolarizing neuromuscular blocking agent has been administered. The methods involve administering a pharmaceutically effective dose of an acetylcholinesterase inhibitor to the subject, where the administration is not via injection. In some embodiments intra-nasal or ocular administration is used.