Masoud Agah

US Patent:

20030233862, Dec 25, 2003

Filed:

May 13, 2003

Appl. No.:

10/437101

Inventors:

Kensall Wise - Ann Arbor MI, US
Richard Sacks - Ann Arbor MI, US
Katharine Beach - Ann Arbor MI, US
Joseph Potkay - Bay Village OH, US
Masoud Agah - Ann Arbor MI, US

International Classification:

G01N030/60

US Classification:

073/023390, 096/104000, 219/209000

Abstract:

A high-sensitivity, separation microcolumn assembly for a microgas chromatograph and the like is provided. The assembly has an ultra-low mass complete with integrated heaters. The assembly uses multiple zones for temperature control, and microstructures that permit very rapid heating and cooling of the microcolumn.

US Patent:

20040255643, Dec 23, 2004

Filed:

Jun 4, 2004

Appl. No.:

10/861036

Inventors:

Kensall Wise - Ann Arbor MI, US
Richard Sacks - Ann Arbor MI, US
Joseph Potkay - Bay Village OH, US
Masoud Agah - Ann Arbor MI, US

International Classification:

G01N030/02

US Classification:

073/023390

Abstract:

A high-performance separation microcolumn assembly and method for making such an assembly are provided. The assembly includes high-performance Si-glass GC separation columns having integrated heaters and temperatures sensors for temperature programming and integrated pressure sensors for flow control. These columns, integrated on a die, are fabricated using a silicon-on-glass dissolved-wafer-process. The TCR of the temperature sensors and the sensitivity of the pressure sensors satisfy the requirements needed to achieve reproducible separations in a GC system. Using these columns, highly-resolved multiple-component separations were obtained with analysis times a factor of two faster than isothermal responses.

US Patent:

20220373518, Nov 24, 2022

Filed:

May 9, 2022

Appl. No.:

17/740319

Inventors:

- Blacksburg VA, US
Masoud AGAH - Blacksburg VA, US

International Classification:

G01N 30/14
G01N 30/62
G01N 30/30
G01N 33/00
B81B 1/00
B81C 1/00

Abstract:

Micro gas chromatographic devices are provided having a microfluidic separation column and a plurality of capillaries where the capillaries have been independently configured in terms of the capillary length, capillary width, the packing density and packing geometry of the capillary using one or more micro pillars, the tortuosity of the capillary path, and the presence and identity of the stationary phase for use in micro gas chromatographic separation of complex mixtures of compounds. Through the plurality of capillaries, the devices are capable of discriminating between complex samples even in instances where complete separation of the components is not possible. Methods of fabrication and methods of use of the devices are also provided. The devices can be readily fabricated using known techniques. The devices can be used for the analysis of complex mixtures of compounds containing tens or hundreds of compounds in which just a few differ in presence or concentration.

US Patent:

20190070587, Mar 7, 2019

Filed:

Aug 3, 2018

Appl. No.:

16/054949

Inventors:

Masoud Agah - Blacksburg VA, US
Muhammad Akbar - Blacksburg VA, US
Apoorva Garg - Blacksburg VA, US
Leyla Nazhandali - Blacksburg VA, US
Hamza Shakeel - Blacksburg VA, US

International Classification:

B01J 20/32
G01N 30/60
B01J 20/22
B01J 20/281

Abstract:

The present invention provides a detector and method for detecting substances in complex mixtures. The detector includes a microfabricated preconcentrator, a separation column with an on-chip thermal conductivity detector, a controller for controlling flow and thermal management and a user interface. The thermal conductivity detector includes a first resistor located at an inlet of the separation column and a second resistor located at an outlet of the separation column.

US Patent:

20180164260, Jun 14, 2018

Filed:

Dec 8, 2017

Appl. No.:

15/836405

Inventors:

Masoud Agah - Blacksburg VA, US
Muhammad Akbar - Blacksburg VA, US
Bishnu Prasad Regmi - Blacksburg VA, US

International Classification:

G01N 30/30
G01N 30/60

Abstract:

A miniaturized gas chromatography system integrated on single chip comprising a sample injection unit, a separation column having an inlet, an exit and an interior surface, at least one detector located at the separation column exit and the sample injection unit having a T-shaped configuration. The column may be coated with room temperature ionic liquids, with and without an intermediate layer between the room temperature ionic liquid and the silicon surface.

US Patent:

20160018365, Jan 21, 2016

Filed:

Jun 12, 2015

Appl. No.:

14/738509

Inventors:

Masoud Agah - Blacksburg VA, US
Muhammad Akbar - Blacksburg VA, US
Apoorva Garg - Blacksburg VA, US
Leyla Nazhandali - Blacksburg VA, US
Hazma Shakeel - Blacksburg VA, US

International Classification:

G01N 30/28
B01J 20/281
B01J 20/32
B01J 20/22

Abstract:

The present invention provides a detector and method for detecting substances in complex mixtures. The detector includes a microfabricated preconcentrator, a separation column with an on-chip thermal conductivity detector, a controller for controlling flow and thermal management and a user interface. The thermal conductivity detector includes a first resistor located at an inlet of the separation column and a second resistor located at an outlet of the separation column.

US Patent:

20150130473, May 14, 2015

Filed:

Oct 31, 2014

Appl. No.:

14/529760

Inventors:

Masoud Agah - Blacksburg VA, US
Shree Narayanan Sreedharan Nair - Hillsboro OR, US

International Classification:

G01N 27/66

US Classification:

324464

Abstract:

The present invention provides an ionization detector having a base having an enclosed chamber. The enclosed chamber has a first end and a second end. The detector also includes a first outlet which is a source of an excitable medium. A second outlet is provided which functions a source of an analyte that is transported by a carrier gas. An ionization source for creating a discharge from said excitable medium is also provided. The collector electrode generates a time dependent current based on its interaction with ionized analytes from which the analyte may be detected.