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Lori Krim Gavrin

age ~49

from Wayne, PA

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Also known as:
  • Lori K Gavrin
  • Andrew S Gavrin
  • Lori D Krim
  • Lori N
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Connected to:

Lori Gavrin Phones & Addresses

  • Wayne, PA
  • 306 Clairemont Rd, Villanova, PA 19085
  • Bryn Mawr, PA
  • Malvern, PA
  • Woburn, MA
  • Holliston, MA
  • Philadelphia, PA
  • Belmont, MA

Us Patents

  • Secondary Amino-And Cycloamino-Cycloalkanol Derivatives And Methods Of Their Use

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  • US Patent:
    7402698, Jul 22, 2008
  • Filed:
    Oct 12, 2004
  • Appl. No.:
    10/962899
  • Inventors:
    Paige Erin Mahaney - Pottstown PA, US
    Michael Byron Webb - Levittown PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    Eugene John Trybulski - Huntingdon Valley PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    C07C 211/00
    A61K 31/135
  • US Classification:
    564336, 564 5, 564363, 560220, 560250, 514649
  • Abstract:
    The present invention is directed to secondary amino- and cycloamino-cycloalkanol derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

  • Fused-Aryl And Heteroaryl Derivatives And Methods Of Their Use

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  • US Patent:
    7419980, Sep 2, 2008
  • Filed:
    Oct 12, 2004
  • Appl. No.:
    10/963064
  • Inventors:
    Eugene John Trybulski - Huntingdon Valley PA, US
    Paige Erin Mahaney - Pottstown PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    Joseph Peter Sabatucci - Collegeville PA, US
    Gary Paul Stack - Ambler PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    A61K 31/497
    A61K 31/4965
    C07D 401/00
    C07D 403/00
    C07D 405/00
    C07D 409/00
    C07D 411/00
    C07D 413/00
    C07D 417/00
    C07D 419/00
    C07D 241/04
    C07D 295/00
  • US Classification:
    51425213, 51425214, 51425301, 51425309, 5142531, 51425311, 51425401, 51425405, 5142541, 51425505, 544360, 544373, 544374, 544379, 544391, 544397, 544403, 544405
  • Abstract:
    The present invention is directed to fused-aryl and heteroaryl derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

  • Alkanol And Cycloalkanol-Amine Derivatives And Methods Of Their Use

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  • US Patent:
    7491723, Feb 17, 2009
  • Filed:
    Oct 12, 2004
  • Appl. No.:
    10/962880
  • Inventors:
    Eugene John Trybulski - Huntingdon Valley PA, US
    Paige Erin Mahaney - Pottstown PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    William Jay Moore - Collegeville PA, US
    Joseph Peter Sabatucci - Collegeville PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    A61K 31/497
    C07D 401/00
    C07D 403/00
    C07D 405/00
    C07D 409/00
    C07D 411/00
    C07D 413/00
    C07D 417/00
    C07D 419/00
    C07D 241/04
    C07D 295/00
  • US Classification:
    51425212, 544360, 544373, 544374, 544379, 544391, 544397, 544403, 544405
  • Abstract:
    The present invention is directed to alkanoyl and cycloalkanoyl-amine derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

  • Phenylpiperazine Cycloalkanol Derivatives And Methods Of Their Use

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  • US Patent:
    7531543, May 12, 2009
  • Filed:
    Oct 12, 2004
  • Appl. No.:
    10/963458
  • Inventors:
    Paige Erin Mahaney - Pottstown PA, US
    Eugene John Trybulski - Huntingdon Valley PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    An Thien Vu - Pottstown PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    A61K 31/4965
    C07D 223/00
    C07D 225/00
    C07D 241/00
    C07D 241/02
    C07D 243/00
    C07D 245/00
  • US Classification:
    51425504, 540450, 540470, 540484, 540553, 544336
  • Abstract:
    The present invention is directed to phenylpiperazine cycloalkanol derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

  • Substituted Aryl Cycloalkanoyl Derivatives And Methods Of Their Use

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  • US Patent:
    7550456, Jun 23, 2009
  • Filed:
    Feb 14, 2008
  • Appl. No.:
    12/031187
  • Inventors:
    Eugene John Trybulski - Huntingdon Valley PA, US
    Joseph Peter Sabatucci - Collegeville PA, US
    An Thien Vu - Pottstown PA, US
    Stephen Todd Cohn - Spring TX, US
    Arthur Attilio Santilli - Havertown PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    Fei Ye - Audubon PA, US
    Paige Erin Mahaney - Pottstown PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    A01N 43/62
    C07D 243/08
  • US Classification:
    514218, 540575
  • Abstract:
    The present invention is directed to substituted aryl cycloalkanoyl derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

  • Substituted N-Heterocycle Derivatives And Methods Of Their Use

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  • US Patent:
    7550485, Jun 23, 2009
  • Filed:
    Oct 12, 2004
  • Appl. No.:
    10/962971
  • Inventors:
    Paige Erin Mahaney - Pottstown PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    Douglas John Jenkins - Collegeville PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    A61K 31/4468
  • US Classification:
    514329, 514316, 514319, 514331, 546223
  • Abstract:
    The present invention is directed to substituted N-heterocycle derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

  • Substituted Aryl Cycloalkanol Derivatives And Methods Of Their Use

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  • US Patent:
    7365076, Apr 29, 2008
  • Filed:
    Oct 12, 2004
  • Appl. No.:
    10/963111
  • Inventors:
    Eugene John Trybulski - Huntingdon Valley PA, US
    Joseph Peter Sabatucci - Collegeville PA, US
    An Thien Vu - Pottstown PA, US
    Stephen Todd Cohn - Reading PA, US
    Arthur Attilio Santilli - Havertown PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    Fei Ye - Audubon PA, US
    Paige Erin Mahaney - Pottstown PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    A61K 31/50
    A61K 31/501
    C07D 241/04
    C07D 295/00
  • US Classification:
    51425212, 544399, 544403
  • Abstract:
    The present invention is directed to substituted aryl cycloalkanoyl derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

  • Substituted N-Heterocycle Derivatives And Methods Of Their Use

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  • US Patent:
    20090227585, Sep 10, 2009
  • Filed:
    May 18, 2009
  • Appl. No.:
    12/467594
  • Inventors:
    Paige Erin Mahaney - Pottstown PA, US
    Lori Krim Gavrin - Philadelphia PA, US
    Douglas John Jenkins - Collegeville PA, US
  • Assignee:
    Wyeth - Madison NJ
  • International Classification:
    A61K 31/495
    C07D 241/04
    C07D 413/06
    A61K 31/5377
    A61P 29/00
    A61P 1/00
  • US Classification:
    5142355, 544396, 544129, 51425504
  • Abstract:
    The present invention is directed to substituted N-heterocycle derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.

Resumes

Lori Gavrin Photo 1

Head Of Strategic Partnerships; Executive Director Of Corporate Development

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Location:
14800 Charlson Rd, Eden Prairie, MN 55347
Industry:
Pharmaceuticals
Work:
Gsk Oct 2016 - Aug 2018
Discovery Partnerships With Academia; Senior Director Collaboration Strategy; Esprit R and D at Gsk
Tmunity Therapeutics Incorporated Oct 2016 - Aug 2018
Head of Strategic Partnerships; Executive Director of Corporate Development
Gsk Aug 2015 - Oct 2016
Discovery Partnerships With Academia; Senior Director Collaboration Strategy; Esprit R and D
2015 Medicinal Chemistry Gordon Research Conference Aug 2012 - Aug 2015
Chair
Gsk Jul 2014 - Aug 2015
Esprit Associate - Scientific Director In Maternal and Neonatal Health R and D
Education:
University of Pennsylvania 1996 - 2001
Doctorates, Doctor of Philosophy, Organic Chemistry Colgate University 1992 - 1996
Bachelors, Bachelor of Science, Organic Chemistry Holliston High School 1988 - 1992
Skills:
Drug Discovery
Drug Design
Medicinal Chemistry
Lead Change
Drug Development
Organic Chemistry
Organic Synthesis
High Throughput Screening
R&D
Parallel Synthesis
Adme
Hplc
Lc Ms
Pharmacology
Assay Development
Chromatography
Chemistry
Bioanalysis
Synthetic Organic Chemistry
Heterocyclic Chemistry
Nmr
Purification
In Vitro
Drug Metabolism
Cheminformatics
Analytical Chemistry
Biomarkers
Mass Spectrometry
Protein Chemistry
Dmpk
Pharmaceutical Research
Small Molecules
Computational Chemistry
Ind
Inflammation
Molecular Modeling
Pharmacokinetics
Structure Elucidation
Lori Gavrin Photo 2

Lori Gavrin

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