Leonard Joseph Brandt

US Patent:

7489964, Feb 10, 2009

Filed:

Nov 29, 2006

Appl. No.:

11/605585

Inventors:

Stephen C. Suffin - Sherman Oaks CA, US
W. Hamlin Emory - Malibu CA, US
Leonard J. Brandt - Laguna Hills CA, US

Assignee:

CNS Response, Inc. - Costa Mesa CA

International Classification:

A61B 5/04
A61K 49/00

US Classification:

600544, 600545, 424 92

Abstract:

A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.

US Patent:

7962204, Jun 14, 2011

Filed:

Nov 18, 2008

Appl. No.:

12/273383

Inventors:

Stephen C. Suffin - Sherman Oaks CA, US
W. Hamlin Emory - Malibu CA, US
Leonard J. Brandt - San Juan Capistrano CA, US

Assignee:

CNS Response, Inc. - Aliso Viejo CA

International Classification:

A61B 5/04

US Classification:

600544, 600545

Abstract:

A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.

US Patent:

8224433, Jul 17, 2012

Filed:

Oct 7, 2009

Appl. No.:

12/575297

Inventors:

Stephen C. Suffin - Sherman Oaks CA, US
W. Hamlin Emory - Malibu CA, US
Leonard J. Brandt - San Juan Capistrano CA, US

Assignee:

CNS Response, Inc. - Costa Mesa CA

International Classification:

A61B 5/00
A61B 5/04

US Classification:

600544, 600300

Abstract:

A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.

US Patent:

20030135128, Jul 17, 2003

Filed:

Jul 11, 2002

Appl. No.:

10/193735

Inventors:

Stephen Suffin - Sherman Oaks CA, US
W. Emory - Malibu CA, US
Leonard Brandt - San Juan Capistrano CA, US

International Classification:

A61B005/00

US Classification:

600/544000, 600/300000

Abstract:

A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.

US Patent:

20050096311, May 5, 2005

Filed:

Oct 30, 2003

Appl. No.:

10/697497

Inventors:

Stephen Suffin - Sherman Oaks CA, US
W. Hamlin Emory - Malibu CA, US
Leonard Brandt - San Juan Capistrano CA, US

Assignee:

CNS Response - Santa Anna CA

International Classification:

A61K031/55
A61K031/137

US Classification:

514217000, 514649000

Abstract:

The present invention contemplates compositions and methods to treat patients having a nervous system disorder with a formulation comprising an anticonvulsant and a neuroactive modulator. Also described is a method to predict the probability of a significant recovery when a treating an individual patient having a nervous system disorder with a formulation comprising an anticonvulsant and a neuroactive modulator. Specifically, methods for predicting patient prognosis include, but are not limited to, quantitative electroencephalography, psychometric test batteries, biological indicators, brain metabolic indicators, genotype profiles, neuroimaging, objective test measurements and multi-modalities. The present invention also discloses a device providing an organized dispensation of the above formulations such that the patient or medical personnel may easily and accurately decrease the daily dosage of a third drug and increase the daily dosage of a formulation comprising an anticonvulsant and a neuroactive modulator.

US Patent:

20050118286, Jun 2, 2005

Filed:

Oct 22, 2004

Appl. No.:

10/972188

Inventors:

Stephen Suffin - Sherman Oaks CA, US
W. Emory - Malibu CA, US
Leonard Brandt - San Juan Capistrano CA, US

International Classification:

A61K038/05
A61K031/5377
A61K031/522
A61K031/445
A61K031/137
A61K031/138
A61K031/403
A61K035/78

US Classification:

424752000, 514018000, 514263310, 514411000, 514317000, 514649000, 514651000, 514618000, 514235500

Abstract:

The present invention contemplates compositions and methods to treat patients having a nervous system disorder with a formulation comprising an anticonvulsant and a neuroactive modulator. Also described is a method to predict the probability of a significant recovery when a treating an individual patient having a nervous system disorder with a formulation comprising an anticonvulsant and a neuroactive modulator. Specifically, methods for predicting patient prognosis include, but are not limited to, quantitative electroencephalography, psychometric test batteries, biological indicators, brain metabolic indicators, genotype profiles, neuroimaging, objective test measurements and multi-modalities. The present invention also discloses a device providing an organized dispensation of the above formulations such that the patient or medical personnel may easily and accurately decrease the daily dosage of a third drug and increase the daily dosage of a formulation comprising an anticonvulsant and a neuroactive modulator.

US Patent:

20090157662, Jun 18, 2009

Filed:

Nov 18, 2008

Appl. No.:

12/273304

Inventors:

Stephen C. Suffin - Sherman Oaks CA, US
W. Hamlin Emory - Malibu CA, US
Leonard J. Brandt - San Juan Capistrano CA, US

International Classification:

G06F 17/30

US Classification:

707 5, 707E17071

Abstract:

A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.