Vaithilingam Sekar - Ames IA, US Bruce Held - Ames IA, US Kyu Chung - Granger IN, US
Assignee:
MS Technologies LLC - West Point IA
International Classification:
C07K 16/00 C12P 21/06 G01N 33/53
US Classification:
5303871, 5303881, 5303885
Abstract:
Antibodies immunoreactive to double mutant EPSPS are provided, and in an embodiment the double mutant EPSPS is one in which the wild-type EPSPS is substituted at residue 102 with isoleucine and at residue 106 with serine. Also provided are hybridomas producing the antibodies, as well as methods of making and using the antibodies.
Gregory M. Landes - The Woodlands TX, US Kyu Chung - Granger IN, US Ling Chen - Blue Bell PA, US Urvi Desai - The Woodlands TX, US David Reed Powell - Houston TX, US Seokjoo Hong - The Woodlands TX, US
Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
Gregory M. Landes - The Woodlands TX, US Kyu Chung - Granger IN, US Ling Chen - Blue Bell PA, US Urvi Desai - The Woodlands TX, US David Reed Powell - Houston TX, US Seokjoo Hong - The Woodlands TX, US
Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
Gregory Landes - The Woodlands TX, US Kyu Chung - Granger IN, US Ling Chen - Blue Bell PA, US Urvi Desai - The Woodlands TX, US David Powell - Houston TX, US Seokjoo Hong - The Woodlands TX, US
International Classification:
A61K 39/395 C07K 16/22
US Classification:
424145100, 530388250
Abstract:
Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided.
Amgen
Scientist
Alliance Pharma Oct 2016 - May 2017
Manager
Novartis Nov 1, 2008 - Aug 2015
Scientist I
Novartis Mar 2015 - May 2015
Internship
Swiss Tropical and Public Health Institute Dec 2013 - Jan 2015
Msc Candidate
Education:
University of Basel 2013 - 2014
Master of Science, Masters, Epidemiology
New York Medical College 1994 - 1996
Master of Science, Masters, Molecular Biology, Biochemistry
Skills:
Drug Discovery Assay Development Elisa Validation Glp Cell Culture Rt Pcr Biotechnology Monoclonal Antibodies Hplc Laboratory Life Sciences Science Western Blotting Immunology Pharmaceutical Industry Pcr Protein Chemistry Biochemistry Protein Purification Cell Biology Sds Page Biac Facs Analysis Msd Luminex Gyros Lc Ms Gcp Affinity Purification Protein Labeling Pbmc Isolation Hybridoma Electronic Lab Notebooks Lims Winnonlin Flowjo Softmax Pro Graphpad Prism Stata R Animal Work Drug Development Good Laboratory Practice