CSO, Translational Science at Eli Lilly and Company
Location:
United States
Industry:
Pharmaceuticals
Work:
Eli Lilly and Company since Sep 2003
CSO, Translational Science
Eli Lilly and Company Feb 2008 - Dec 2009
CSL, Integrative Biology
Eli Lilly and Company Oct 2006 - Jan 2008
Research Fellow
Eli Lilly and Company Oct 2004 - Sep 2006
Senior Research Advisor
Eli Lilly and Company Aug 2003 - Sep 2004
Research Advisor
Education:
University of Utah 1985 - 1989
PhD, Neuropharmacology
Isbn (Books And Publications)
Pharmacological Regulation Of Gene Expression In The Cns: Towards An Understanding Of Basal Ganglial Functions
Ruth Elizabeth TenBrink - Kalamazoo MI, US Kalpana M. Merchant - Portage MI, US Timothy J. McCarthy - Webster Groves MO, US
Assignee:
Pharmacia & Upjohn Company - Kalamazoo MI
International Classification:
C07D498/06 A61K031/5365
US Classification:
424 944, 424 181, 544 99
Abstract:
The present invention provides isotopically labeled oxazinocarbazole derivatives having a ring connecting position 8 (C-8) and position 9 (N-9), and more specifically, provides compounds of formula (I) wherein R, R, Rand Rare described herein. These compounds are useful in the diagnostic analysis of diseases wherein modulation of 5-HT activity is desired.
1,2,3,4,5,6-Hexahydroazepino[4,5-B]Indoles Containing Arylsulfones At The 9-Position
The present invention discloses radioligands of 9-arylsulfone of the formula (X) or a pharmaceutically acceptable salt or enantiomer thereof, which are useful in diagnosing depression, obesity and other CNS disorders.
Susan Jacobsen - Richland MI, US Kalpana Merchant - Portage MI, US Eric Jacobsen - Richland MI, US
International Classification:
A61K031/55 C07D487/02
US Classification:
514/215000, 540/586000
Abstract:
The present invention provides pharmaceutically active compounds of formula I as described herein useful for the treatment of diseases or disorders of the central nervous system.
The present invention provides genes encoding heretofore unknown G protein-coupled receptors, constructs and recombinant host cells incorporating the genes; the GPCR polypeptides encoded by the genes; antibodies to the polypeptides; and methods of making and using all of the foregoing.
1,2,3,4,5,6-Hexahydroazepino[4,5-B]Indoles Containing Arylsulfones At The 9-Position
Eric Jacobsen - Chesterfield MO, US Kalpana Merchant - Zionsville IN, US
International Classification:
A61K031/55 C07D487/02
US Classification:
514/215000, 540/577000
Abstract:
The present invention discloses radioligands of 9-arylsulfone of the formula (X) or a pharmaceutically acceptable salt or enantiomer thereof, which are useful in diagnosing depression, obesity and other CNS disorders.
Donmienne Doen Mun Leung - San Diego CA, US Jirong Lu - Carmel IN, US Kalpana Mahesh Merchant - Zionsville IN, US Mahmoud Ghanem - Indianapolis IN, US Linda Maureen O'Bryan - Indianapolis IN, US Rosamund Carol Smith - Greenfield IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07K 14/47
US Classification:
514 177, 530350
Abstract:
The present invention relates to novel variants of human glial cell-derived neurotrophic factor (GDNF) and methods for their use.