Justin M Ferrentino

US Patent:

20210259240, Aug 26, 2021

Filed:

Feb 19, 2021

Appl. No.:

17/180506

Inventors:

- Manchester NH, US
Timothy D. Moreau - Manchester NH, US
Scott A. Coull - Manchester NH, US
Piper L. Curtis - Manchester NH, US
Justin M. Ferrentino - Mont Vernon NH, US
Steve L. Henning - Manchester NH, US
Bradley Hovan - Manchester NH, US
Stuart A. Jacobson - Lexington MA, US
Katie E. Leon - Ashland MA, US
Katelyn Mosle - New Boston NH, US

International Classification:

A01N 1/02

Abstract:

System and method for maintaining an organ and transporting the organ from a donor to a recipient, maintaining normothermic temperature of the organ. The system includes a circulation system providing oxygenated perfusate to the organ and enabling continuous monitoring of the perfusate moving through the organ. The tank can provide an inlet that can accept selected infusible materials, and an outlet that can enable sampling and waste removal. The system can continually monitor the solution bath in which the organ is bathed, and the system can manage the composition of the gas in the tank.

US Patent:

20200392450, Dec 17, 2020

Filed:

Jun 17, 2020

Appl. No.:

16/904198

Inventors:

- Manchester NH, US
Stephanie M. Miskell - Weare NH, US
Zachary T. Kops - Watertown MA, US
Justin M. Ferrentino - Mont Vernon NH, US
Michael C. Tilley - Amherst NH, US
Andrew K. Capulli - Auburn NH, US
Keira L McGrath - Manchester NH, US
Stuart A. Jacobson - Lexington MA, US

International Classification:

C12M 1/36
C12M 3/06
C12M 1/00
B01L 3/00
G01N 35/10
C12M 1/02
C12M 1/12
B01L 9/06
G01N 35/00
C12M 1/26
C12M 1/34

Abstract:

Manufacturing system and method for creating multiple tissue constructs from cells. System can include a thaw subsystem (if the cells are provided in a frozen state), an expansion subsystem, a concentration subsystem, and a tissue maturation subsystem. Each of these subsystems is modular and can be reconfigured, and the process can be repeated depending on the specific tissue process being implemented. Multiple tissue types can be combined in multiple bioreactors. The activities of multiple bioreactors can be coordinated and controlled in an automated manner by a supervisor controller. The supervisor controller can receive user input at the start of the process, and can manage the process henceforth, alerting the user if user actions are required.