Eugene J Wu

US Patent:

20070003923, Jan 4, 2007

Filed:

Jun 10, 2004

Appl. No.:

10/560250

Inventors:

Glen Nemerow - Encinitas CA, US
Eugene Wu - Oceanside CA, US
Phoebe Stewart - Brentwood TN, US

Assignee:

SCRIPPS RESEARCH INSTITUTE, THE - LAJOLLA CA
REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE - OAKLAND CA

International Classification:

C12Q 1/70
C12N 7/00
C12N 15/861
C07K 14/075

US Classification:

435005000, 435456000, 435235100, 530350000, 977802000, 435325000

Abstract:

Recombinant detargeted and retargeted adenovirus viral particles and vectors are provided. In particular, modified fibers from adenoviruses that bind to coxsackie-adenovirus receptor (CAR) in vivo that contain modifications in the fiber shaft are provided. Adenovirus (Ad) particles that express such fibers exhibit reduced binding to CAR. Hence detargeted Ad particles are provides; also provided are retargeted particles.

US Patent:

7576941, Aug 18, 2009

Filed:

Oct 26, 2007

Appl. No.:

11/924830

Inventors:

Teddy T. C. Chen - Huntington Beach CA, US
Eugene Chun-Tsing Wu - Irvine CA, US
John Yin Kwong Li - Laguna Niguel CA, US
Jie Yu - Irvine CA, US
Jonathan V. Nguyen - Laguna Niguel CA, US
Tuong M. Vu - Lake Forest CA, US
Guoxiao Guo - Foothill Ranch CA, US

Assignee:

Western Digital Technologies, Inc. - Lake Forest CA

International Classification:

G11B 5/596

US Classification:

360 7704, 360 7708

Abstract:

A disk drive is disclosed comprising a plurality of servo sectors that define a plurality of tracks, and a head comprising a read element radially offset from a write element. The read element is positioned over a first track, and the first track is read to generate first read wedge repeatable runout (WRRO) values. A first seek operation of the head positions the read element over a second track, and the second track is read to generate first write WRRO values. The first write WRRO values are used to write the first read WRRO values to the first track. A second seek operation of the head positions the read element over a third track, and the third track is read to generate second write WRRO values. The second write WRRO values are used to write the first write WRRO values to the second track.