Guolin Li - Montvale NJ, US Reza Fathi - HoHoKus NJ, US Zhen Yang - Ridgewood NJ, US Yun Liao - Glenrock NJ, US Qiang Zhu - Edson NJ, US Angela Lam - Fort Lee NJ, US Anthony Sandrasagra - Princeton NJ, US Kenneth Nawoschik - Spring Valley NY, US Hyun-Joon Cho - Spring Valley NY, US Jie Cao - White Plains NY, US C. Richard Wobbe - Lexington MA, US Yixin Liu - Rancho Cucamonga CA, US
Aryl substituted pyrazole derivatives are provided, as well as processes for their preparation. The invention also provides compositions and methods for the treatment of HCV by administering a compound of the present invention, alone or in combination with additional antiviral agents, in a therapeutically effective amount.
Monell Chemical Senses Center Philadelphia, PA 2004 to 2012 Research Associate
Education:
Rutgers, the State University of New Jersey - Thesis: Neurogenesis and cell death after brain injury in the adult ring dove Newark, NJ 2001 PhD in PsychologyPeking University - Thesis: Construction of porcine genomic library and screening for growth hormone gene BS in Biology
Skills:
MOLECULAR BIOLOGY DNA / RNA preparations (tissue / single cell) Molecular cloning, tissue / type-specific cell cDNA library construction and screening Eucaryotic expression vector design and construction PCR, RT-PCR, QPCR, RT-QPCR Southern / Northern / In situ hybridization using (non-)radioactive DNA / cRNA probes Immunofluorescent / immunohistochemical staining SDS-PAGE, Western blots, ELISA Other biochemical separation / analytical methods Use of bioinformatics database and tools HISTOLOGY, TISSUE / CELL PREPARATION AND CELL CULTURE Small animal surgery, perfusion, histology Mouse / rat / dog / cat tongue and gut epithelial tissue isolation Primary taste bud cell isolation, culture and calcium imaging Xenopus oocyte isolation, microinjection and culture Transfection and culture of HEK / Sf9 cells ELECTROPHYSIOLOGY Patch clamp 2-electrode voltage clamp COMPUTER Proficient in using softwares in Windows, Mac, Linux / Unix environment Extract and analyze data from genome-wide databases using perl/bioperl, R Familiar to major online bioinformatic databases and open source tools