Jessica L Rennert

US Patent:

6456870, Sep 24, 2002

Filed:

Feb 25, 2000

Appl. No.:

09/514039

Inventors:

Jessica Rennert - Scottsdale AZ
Glenn Aaron Kees - Tempe AZ
Timothy L. Ruchti - Gilbert AZ

Assignee:

Sensys Medical, Inc. - Chandler AZ

International Classification:

A61B 500

US Classification:

600475, 600310

Abstract:

A novel approach to measuring the overall and layer-by-layer thickness of in vivo skin tissue based on near infrared absorbance spectra is described. The different biological and chemical compounds present in the various layers of a tissue sample have differing absorbance spectra and scattering properties that enable them to be discerned and quantified, thus allowing an estimate of the thickness of the tissue being sampled. The method of the invention also yields the chemical composition of the absorbing and/or scattering species of each layer. Additionally, a method of path length normalization for the purpose of noninvasive analyte prediction on the basis of skin thickness and layer constituents is provided.

US Patent:

6501982, Dec 31, 2002

Filed:

Jan 19, 2000

Appl. No.:

09/487236

Inventors:

Timothy L. Ruchti - Gilbert AZ
Suresh Thennadil - Tempe AZ
Stephen F. Malin - Glendale CA
Jessica Rennert - Scottsdale AZ

Assignee:

Sensys Medical, Inc. - Chandler AZ

International Classification:

A61B 600

US Classification:

600473, 600322, 600310, 600475

Abstract:

Noninvasive instrumentation and procedures have been developed for estimating the apparent age of human and animal subjects based on the irradiation of skin tissue with near-infrared light. The method of age estimation provides additional information about primary sources of systematic tissue variability due to chronological factors and environmental exposure. Therefore, categorization of subjects on the basis of the estimated apparent age is suitable for further spectral analysis and the measurement of biological and chemical compounds, such as blood analytes. Furthermore, age determination of subjects has particular benefit in assessment of therapies used to reduce the effects of ageing in tissue and measurement of tissue damage.

US Patent:

6671542, Dec 30, 2003

Filed:

Sep 5, 2002

Appl. No.:

10/237457

Inventors:

Jessica Rennert - Scottsdale AZ
Glenn Aaron Kees - Tempe AZ
Timothy L. Ruchti - Gilbert AZ

Assignee:

Saensys Medical, Inc. - Chandler AZ

International Classification:

A61B 500

US Classification:

600475, 600310

Abstract:

A novel approach to measuring the overall and layer-by-layer thickness of in vivo skin tissue based on near infrared absorbance spectra is described. The different biological and chemical compounds present in the various layers of a tissue sample have differing absorbance spectra and scattering properties that enable them to be discerned and quantified, thus allowing an estimate of the thickness of the tissue being sampled. The method of the invention also yields the chemical composition of the absorbing and/or scattering species of each layer. Additionally, a method of path length normalization for the purpose of noninvasive analyte prediction on the basis of skin thickness and layer constituents is provided.