Chia-Yang Lin - Mountain View CA, US Arnon Rosenthal - Woodside CA, US Jennifer Stratton - Belmont CA, US
International Classification:
A61K 38/00 A61K 39/395 A61P 3/04
US Classification:
424158100, 514012000
Abstract:
This invention relates to methods for treating unwanted body weight loss (such as with cachexia and with aging), eating disorders (such as anorexia nervosa), or opioid-induced emesis by peripheral administration of a trkB agonist. The invention also relates to compositions and kits comprising a trkB agonist.
Methods Of Treating Obesity Or Diabetes Using Nt-4/5
Arnon Rosenthal - Woodside CA, US John C. Lin - Palo Alto CA, US Jennifer R. Stratton - Belmont CA, US Robert D. Klein - Palo Alto CA, US Jaume Pons - San Bruno CA, US
International Classification:
A61K 38/12
US Classification:
514 12
Abstract:
The invention concerns methods for treating obesity, non-insulin dependent diabetes mellitus, metabolic syndrome, and other related diseases by administering an NT-4/5 polypeptide. The invention also concerns compositions and kits comprising an NT-4/5 polypeptide.
Methods For Treating Unwanted Weight Loss Or Eating Disorders By Administering A Trkb Agonist
Chia-Yang Lin - Palo Alto CA, US Arnon Rosenthal - Woodside CA, US Jennifer Renee Stratton - Belmont CA, US
International Classification:
A61K 38/18 A61P 3/04
US Classification:
514 12
Abstract:
This invention relates to methods for treating unwanted body weight loss (such as cachexia), eating disorders (such as anorexia nervosa), or opioid-induced emesis by peripheral administration of a trkB agonist. The invention also relates to compositions and kits comprising a trkB agonist.
Chia-Yang Lin - Palo Alto CA, US Javier Fernando Chaparro Riggers - San Mateo CA, US Ruslan Nikolaevich Grishanin - San Francisco CA, US Jennifer Renee Stratton - Belmont CA, US Wenwu Zhai - Redwood City CA, US
The present invention provides TrkB agonist antibodies. The invention further relates to therapeutic methods for use of these antibodies and antigen-binding portions thereof to improve nerve function, including treatment of peripheral neuropathies, such as Charcot-Marie-Tooth disease.
Methods Of Treating Obesity Or Diabetes Using Nt-4/5
Arnon Rosenthal - Woodside CA, US John Lin - Mountain View CA, US Jennifer Stratton - Belmont CA, US Robert Klein - Palo Alto CA, US Jaume Pons - San Carlos CA, US
International Classification:
A61K038/17
US Classification:
514012000
Abstract:
The invention concerns methods for treating obesity, non-insulin dependent diabetes mellitus, metabolic syndrome, and other related diseases by administering an NT-4/5 polypeptide. The invention also concerns compositions and kits comprising an NT-4/5 polypeptide.
Antibody Variants Transmigrating The Blood-Brain Barrier And Uses Thereof
- Ottawa, CA - Frazer PA, US Kristin Kemmerich - Ottawa, CA David Wilson - Redwood City CA, US Jennifer Stratton - Redwood City CA, US Matthew Pollard - Pullenvale, AU Adam Clarke - Sydney, AU
Assignee:
National Research Council of Canada - Ottawa ON Cephalon, Inc. - Frazer PA
International Classification:
C07K 16/28 A61K 47/68
Abstract:
The present invention relates, in general, to polypeptides capable of transmigrating the blood-brain barrier, and uses thereof. More specifically, the present invention relates to polypeptides derived by site-directed mutagenesis of an existing antibody fragment and uses thereof, and methods of making such molecules. The polypeptides of the present invention show enhanced blood-brain barrier crossing and brain exposure levels in vitro and in vivo.
Stratton Strategies
Principal
Texas Alliance For Life Jan 2005 - Jul 2005
Communications Director
United States Senate Jun 2000 - May 2004
Staff Assistant
Stratspeak Jun 2000 - May 2004
President and Chief Executive Officer
Education:
Mckendree University 1996 - 2000
Bachelors, Bachelor of Arts, Political Science
Skills:
Microsoft Office Microsoft Excel Microsoft Word Customer Service Powerpoint English Windows Research Outlook Teaching Public Speaking Strategic Planning Negotiation Editing Speech Writing
People Skills Organizing Credit Analysis Customer Service Lease Negotiations Management Time Management Marketing Sales Real Estate Business Development Research Contract Negotiation Property Management Team Building Budgeting Budget Management Capital Projects Communication Financial Performance