Jagdeep S Sandhu

US Patent:

8591915, Nov 26, 2013

Filed:

Jul 29, 2011

Appl. No.:

13/194194

Inventors:

Dennis E. Buetow - Champaign IL, US
Schuyler S. Korban - Champaign IL, US
Jagdeep Sandhu - Urbana IL, US
Sergei F. Krasnyanski - Raleigh NC, US

International Classification:

A61K 39/155

US Classification:

4242111

Abstract:

A plant-derived vaccine against respiratory syncytial virus (RSV) is disclosed. The vaccine includes an immunogenic complex that includes plant cells transformed with a chimeric gene containing a nucleotide sequence adapted for protein expression in plants and an RSV coding sequence that encodes an antigenic protein of RSV. Also disclosed are methods of making the plant-derived vaccine of the invention, as well as transgenic plants, transgenic plant cells, and nucleic acid constructs useful in immunizing a mammal against RSV.

US Patent:

20050129704, Jun 16, 2005

Filed:

Sep 23, 2004

Appl. No.:

10/947211

Inventors:

Dennis Buetow - Champaign IL, US
Schuyler Korban - Champaign IL, US
Jagdeep Sandhu - Urbana IL, US
Sergei Krasnyanski - Urbana IL, US

Assignee:

The Board of Trustees of the University of Illinois - Urbana IL

International Classification:

C12Q001/70
A61K039/12
A01H001/00
C12N015/82

US Classification:

424186100, 800288000, 435005000, 530350000

Abstract:

A plant-derived vaccine against respiratory syncytial virus (RSV) is disclosed. The vaccine includes an immunogenic complex that includes plant cells transformed with a chimeric gene containing a nucleotide sequence adapted for protein expression in plants and an RSV coding sequence that encodes an antigenic protein of RSV. Also disclosed are methods of making the plant-derived vaccine of the invention, as well as transgenic plants, transgenic plant cells, and nucleic acid constructs useful in immunizing a mammal against RSV.

US Patent:

20110076302, Mar 31, 2011

Filed:

Jul 30, 2010

Appl. No.:

12/847401

Inventors:

Dennis E. Buetow - Champaign IL, US
Schuyler S. Korban - Champaign IL, US
Jagdeep Sandhu - Urbana IL, US
Sergei F. Krasnyanski - Raleigh NC, US

International Classification:

A61K 39/155
C07H 21/04
C12N 5/14
A01H 5/00
C07K 14/135
A61P 31/14

US Classification:

4241921, 536 234, 435419, 800298, 530350

Abstract:

A plant-derived vaccine against respiratory syncytial virus (RSV) is disclosed. The vaccine includes an immunogenic complex that includes plant cells transformed with a chimeric gene containing a nucleotide sequence adapted for protein expression in plants and an RSV coding sequence that encodes an antigenic protein of RSV. Also disclosed are methods of making the plant-derived vaccine of the invention, as well as transgenic plants, transgenic plant cells, and nucleic acid constructs useful in immunizing a mammal against RSV.