Irini Akritopoulou Zanze from 1817 S Waxwing Ln, Green Oaks, IL 60048, age 58, Phone: 8473677548

Antibacterial Compounds With Activity Against Penicillin-Resistant Streptococcus Pneumoniae
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US Patent:

20040009932, Jan 15, 2004
Filed:

Apr 23, 2003
Appl. No.:

10/421460
Inventors:

Kathleen Phelan - Gurnee IL, US
Stevan Djuric - Libertyville IL, US
Zhenkun Ma - Dallas TX, US
Thomas Marron - Libertyville IL, US
Hong Yong - Grayslake IL, US
Irini Zanze - Lake Bluff IL, US
International Classification:

C07H017/08
A61K031/7048
US Classification:

514/029000, 536/007400
Abstract:

Compounds which are useful as antibacterials for penicillin-resistant and having formula (I) and formula (II) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections using the compounds are disclosed.

Substituted 7,8-Dihydro-1Hpyrimido[4,5-B]Diazepin-4-Amines Are Novel Kinase Inhibitors
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US Patent:

20110105476, May 5, 2011
Filed:

Oct 29, 2009
Appl. No.:

12/608546
Inventors:

Vijaya J. Gracias - West Newton MA, US
Celerino Abad-Zapatero - Lake Forest IL, US
Stevan W. Djuric - Libertyville IL, US
Zhiqin Ji - Libertyville IL, US
Michael R. Michaelides - Libertyville IL, US
Kent D. Stewart - Gurnee IL, US
Irini Zanze - Libertyville IL, US
Assignee:

ABBOTT LABORATORIES - Abbott Park IL
International Classification:

A61K 31/551
C07D 487/02
A61P 35/00
US Classification:

514221, 540568
Abstract:

Compounds having the Formula (I)are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Isoindoline Derivatives, Pharmaceutical Compositions Containing Them, And Their Use In Therapy
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US Patent:

20130210880, Aug 15, 2013
Filed:

Feb 11, 2013
Appl. No.:

13/764454
Inventors:

Michael OCHSE - Ludwigshafen, DE
Frauke POHLKI - Ludwigshafen, DE
Charles W. HUTCHINS - Green Oaks IL, US
Irini ZANZE - Libertyville IL, US
Hongyu H. ZHAO - Libertyville IL, US
Ying X. WANG - Libertyville IL, US
Assignee:

AbbVie Inc. - North Chicago IL
AbbVie Deutschland GmbH & Co. KG - Wiesbaden
International Classification:

C07D 209/46
C07D 405/14
C07D 403/12
US Classification:

514397, 514407, 514416, 5483121, 5483647, 548472
Abstract:

The present invention relates to isoindoline derivatives of the formula (I)or a physiologically tolerated salt thereof.The present invention also relates to pharmaceutical compositions comprising such isoindoline derivatives, and the use of such isoindoline derivatives for therapeutic purposes.

Substituted 7,8-Dihydro-1H-Pyrimido[4,5-B][1,4]Diazepin-4-Amines Are Novel Kinase Inhibitors
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US Patent:

7795248, Sep 14, 2010
Filed:

May 12, 2006
Appl. No.:

11/432931
Inventors:

Vijaya J. Gracias - Lindenhurst IL, US
Celerino Abad-Zapatero - Lake Forest IL, US
Stevan W. Djuric - Libertyville IL, US
Zhiqin Ji - Libertyville IL, US
Michael R. Michaelides - Libertyville IL, US
Kent D. Stewart - Gurnee IL, US
Irini Zanze - Libertyville IL, US
Assignee:

Abbott Laboratories, Inc. - Abbott Park IL
International Classification:

A61K 31/55
C07D 487/00
A61P 37/00
A61P 35/04
US Classification:

514221, 540568
Abstract:

Compounds having the Formula (I).

Pyrrolidine Derivatives, Pharmaceutical Compositions Containing Them, And Their Use In Therapy
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US Patent:

20140275086, Sep 18, 2014
Filed:

Mar 17, 2014
Appl. No.:

14/215533
Inventors:

- North Chicago IL, US
- Wiesbaden, DE
Udo Lange - Ludwigshafen, DE
Ying X. Wang - Libertyville IL, US
Hongyu H. Zhao - Libertyville IL, US
Jason T. Brewer - Zion IL, US
Irini Zanze - Libertyville IL, US
Justin Dietrich - Abbott Park IL, US
Anil Vasudevan - Union Grove WI, US
Stevan W. Djuric - Libertyville IL, US
Yanbin Lao - Abbott Park IL, US
Charles W. Hutchins - Green Oaks IL, US
International Classification:

C07D 207/09
C07D 401/12
C07D 207/48
C07D 401/14
C07D 403/14
C07D 487/04
C07D 487/10
C07D 417/14
C07D 409/14
C07D 495/04
C07D 471/04
C07D 403/12
C07D 405/14
US Classification:

5142358, 5483147, 514402, 548567, 514428, 5483641, 514407, 5462764, 514343, 548542, 514424, 5462744, 514341, 544331, 514275, 544238, 51425205, 544122
Abstract:

The present invention relates to pyrrolidine derivatives of the formula (I),or a physiologically tolerated salt thereof.The invention relates to pharmaceutical compositions comprising such pyrrolidine derivatives, and the use of such pyrrolidine derivatives for therapeutic purposes. The pyrrolidine derivatives are GlyT1 inhibitors.

Pyrrolidine Derivatives, Pharmaceutical Compositions Containing Them, And Their Use In Therapy
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US Patent:

20140275087, Sep 18, 2014
Filed:

Mar 17, 2014
Appl. No.:

14/216222
Inventors:

- North Chicago IL, US
- Wiesbaden, DE
Udo Lange - Ludwigshafen, DE
Ying X. Wang - Libertyville IL, US
Hongyu H. Zhao - Libertyville IL, US
Jason T. Brewer - Zion IL, US
Irini Zanze - Libertyville IL, US
Justin Dietrich - Abbott Park IL, US
Anil Vasudevan - Union Grove WI, US
Stevan W. Djuric - Libertyville IL, US
Yanbin Lao - Abbott Park IL, US
Charles W. Hutchins - Green Oaks IL, US
International Classification:

C07D 207/48
C07D 403/14
C07D 401/14
C07D 403/12
C07D 401/12
US Classification:

5142358, 5483147, 514397, 548542, 514424, 5483641, 514407, 5462784, 514343, 5462744, 514341, 544297, 514275, 546167, 514314, 546143, 514307, 5483131, 514390, 544238, 51425205, 544405, 51425505, 544122
Abstract:

The present invention relates to pyrrolidine derivatives of the formula (I),The invention relates to pharmaceutical compositions comprising such pyrrolidine derivatives, and the use of such pyrrolidine derivatives for therapeutic purposes. The pyrrolidine derivatives are GlyT1 inhibitors.

Irini Akritopoulou Zanze