Ralph M. Albrecht - Belleville WI, US Irawati Kandela - Madison WI, US
International Classification:
A61K 9/51 A61P 43/00
US Classification:
424490, 977906
Abstract:
The present invention provides systems that include magnetic colloidal particles of differing elemental compositions with differing morphologies. The colloidal particles comprise a magnetic material and a shell that surrounds the magnetic material. The colloidal particles can be inductively heated using a magnetic field. The present invention also provides applications of such colloidal particles, such as methods for cytotoxicity and for drug delivery.
Fluorescent Imaging Of Tumors Using Phospholipid Ether Compounds
Anatoly PINCHUK - Madison WI, US Jamey P. WEICHERT - Fitchburg WI, US Marc LONGINO - Verona WI, US Irawati KANDELA - Madison WI, US William R. CLARKE - Colgate WI, US
International Classification:
A61K 49/00
US Classification:
424 96
Abstract:
The invention generally relates to the use of novel fluorescent phospholipid ether compounds and compositions comprising these compounds in fluorescence imaging of tumors. A preferred compound of the present invention has the following structural formula:
Fluorescent Imaging Of Skin Cancers Using Phospholipid Ether Compounds
Anatoly Pinchuk - Madison WI, US Jamey P. Weichert - Fitchburg WI, US Marc Longino - Verona WI, US Irawati Kandela - Madison WI, US William R. Clarke - Colgate WI, US
International Classification:
A61B 5/00
US Classification:
424 96
Abstract:
The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and their use in a variety of diagnostic applications, including fluorescence imaging of tumors. A preferred compound of the present invention has the following structural formula:
Fluorescent Phospholipid Ether Compounds, Compositions, And Methods Of Use
Anatoly Pinchuk - Madison WI, US Jamey P. Weichert - Fitchburg WI, US Marc Longino - Verona WI, US Irawati Kandela - Madison WI, US William R. Clarke - Colgate WI, US
International Classification:
A61K 49/00 C07F 9/06 C07F 5/02
US Classification:
424 96, 564 15, 546 22, 548405, 548414
Abstract:
The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and their use in a variety of diagnostic applications, including fluorescence imaging of tumors. A preferred compound of the present invention has the following structural formula:
Use Of Fluorescent Phospholipid Ether Compounds In Biopsies
Anatoly PINCHUK - Madison WI, US Jamey P. WEICHERT - Fitchburg WI, US Marc LONGINO - Verona WI, US Irawati KANDELA - Madison WI, US William R. CLARKE - Colgate WI, US
International Classification:
A61B 6/00 A61K 49/00
US Classification:
600431, 424 96
Abstract:
The invention generally relates to the use of novel fluorescent phospholipid compounds and compositions comprising these compounds in biopsy applications. A preferred compound of the present invention has the following structural formula:
Ether And Alkyl Phospholipid Compounds For Treating Cancer And Imaging And Detection Of Cancer Stem Cells
Jamey P. Weichert - Fitchburg WI, US Anatoly Pinchuk - Madison WI, US Irawati Kandela - Madison WI, US Marc Longino - Verona WI, US William R. Clarke - Colgate WI, US
International Classification:
A61K 51/00 C12Q 1/02 A61P 35/04
US Classification:
424 177, 435 29
Abstract:
Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem cells in humans.
Non-Radioactive Phospholipid Compounds, Compositions, And Methods Of Use
Anatoly Pinchuk - Madison WI, US Marc Longino - Verona WI, US Jamey P. Weichert - Fitchburg WI, US William R. Clarke - Colgate WI, US Abram M. Vaccaro - Stoughton WI, US Irawati Kandela - Madison WI, US
International Classification:
A61K 51/04 A61K 31/685 A61K 31/688 A61P 35/00
US Classification:
424 177, 514 77
Abstract:
The present invention provides phospholipid ether and alkyl phospholipid compounds and their combinations with other cancer therapy agents. More specifically, the invention relates to the use of phospholipid ether compounds comprising a “cold” isotope of iodine, e.g. I, or H, for treating cancer and combinations of phospholipid compounds comprising radioactive (i.e., “hot”) and non-radioactive (i.e., “cold”) isotopes of iodine.
Colloidal Magnetic Nanobioparticles For Cytotoxicity And Drug Delivery
Ralph M. Albrecht - Belleville WI, US Irawati Kandela - Madison WI, US
International Classification:
C12N 5/071 G01N 33/53
US Classification:
435325, 436501
Abstract:
The present invention provides systems that include magnetic colloidal particles of differing elemental compositions with differing morphologies. The colloidal particles comprise a magnetic material and a shell that surrounds the magnetic material. The colloidal particles can be inductively heated using a magnetic field. The present invention also provides applications of such colloidal particles, such as methods for cytotoxicity and for drug delivery.