Igor Bacik from 13001 Crookston Ln APT 34, Rockville, MD 20851, age 72, Phone: 3017704651

Plasmodium Liver Stage Antigens
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US Patent:

7722889, May 25, 2010
Filed:

Sep 29, 2006
Appl. No.:

12/088065
Inventors:

Patrick Duffy - Seattle WA, US
Urszula Krzych - Washington DC, US
Vladislav A. Malkov - Seattle WA, US
Jason W. Wendler - Lincoln NE, US
Igor Bacik - Rockville MD, US
Assignee:

Seattle Biomedical Research Institute - Seattle WA
The United States of America as represented by the Secretary of the Army - Washington DC
International Classification:

A61K 39/015
C07K 14/445
C07H 21/04
C12P 21/04
US Classification:

4242681, 4242651, 4241911, 530350, 530300, 435 697, 435 691, 536 237, 536 235
Abstract:

The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.

Immunogenic Chimeras Comprising Nucleic Acid Sequences Encoding Endoplasmic Reticulum Signal Sequence Peptides And At Least One Other Peptide, And Their Uses In Vaccines And Disease Treatments
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US Patent:

58561870, Jan 5, 1999
Filed:

Jun 5, 1995
Appl. No.:

8/461566
Inventors:

Nicholas P. Restifo - Washington DC
Steven A. Rosenberg - Bethesda MD
Jack R. Bennick - Olney MD
Igor Bacik - Rockville MD
Jonathan W. Yewdell - Silver Springs MD
Assignee:

The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:

C12N 506
C12N 508
US Classification:

4353723
Abstract:

Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.

Immunogenic Chimeras Comprising Nucleic Acid Sequences Encoding Endoplasmic Reticulum Signal Sequence Peptides And At Least One Other Peptide, And Their Uses In Vaccines And Disease Treatments
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US Patent:

58465405, Dec 8, 1998
Filed:

Jun 6, 1995
Appl. No.:

8/471341
Inventors:

Nicholas P. Restifo - Washington DC
Steven A. Rosenberg - Bethesda MD
Jack R. Bennink - Olney MD
Igor Bacik - Rockville MD
Jonathan W. Yewdell - Silver Springs MD
Assignee:

The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:

A61K 3900
A61K 3902
C12N 1563
C07H 2104
US Classification:

4241921
Abstract:

Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.

Immunogenic Chimeras Comprising Nucleic Acid Sequences Encoding Endoplasmic Reticulum Signal Sequence Peptides And At Least One Other Peptide, And Their Uses In Vaccines And Disease Treatments
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US Patent:

57335486, Mar 31, 1998
Filed:

Jun 5, 1995
Appl. No.:

8/464318
Inventors:

Nicholas P. Restifo - Washington DC
Steven A. Rosenberg - Bethesda MD
Jack R. Bennink - Olney MD
Igor Bacik - Rockville MD
Jonathan W. Yewdell - Silver Springs MD
Assignee:

The Government of the United States of America, as represented by the
Secretary of the Department of Health and Human Services - Washington DC
International Classification:

A61K 3900
A61K 3802
C07K 200
US Classification:

4241841
Abstract:

Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.

Plasmodium Liver Stage Antigens
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US Patent:

20100166794, Jul 1, 2010
Filed:

Mar 11, 2010
Appl. No.:

12/722439
Inventors:

Patrick Duffy - Seattle WA, US
Stefan H.I. Kappe - Seattle WA, US
Urszula Krzych - Washington DC, US
Lawrence W. Bergman - Landsdale PA, US
Vladislav A. Malkov - Seattle WA, US
Alice Tarun - Shoreline WA, US
Jason W. Wendler - Lincoln NE, US
Igor Bacik - Rockville MD, US
Assignee:

SEATTLE BIOMEDICAL RESEARCH INSTITUTE - Seattle WA
The USA, as Represented by the Secretary of the Army,on Behalf of the Walter Reed - Fort Detrick MD
Philadelphia Health & Education Corporation, d/b/a Drexel University College of Medicine "DUCOM" - Philadelphia PA
International Classification:

A61K 39/002
C07K 14/445
C07H 21/04
A61P 33/06
US Classification:

4241911, 530350, 536 237
Abstract:

The invention provides isolated liver stage polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage polypeptides of the invention, compositions comprising one or more liver stage polypeptides of the invention, methods for inducing an immune response against the liver stage polypeptides, and methods for treating and diagnosing liver stage malaria.

Igor Bacik