Hamid Shir Shirkhan

US Patent:

6783668, Aug 31, 2004

Filed:

Oct 9, 2003

Appl. No.:

10/682684

Inventors:

Hamid Shirkhan - Newton MA

Assignee:

Fluid Management Systems, Inc. - Waltham MA

International Classification:

G01N 118

US Classification:

210137, 210177, 2101982, 436161, 422 69

Abstract:

A system for pressurized liquid extraction and purification of solid samples includes a pressurized liquid extraction (PLE) module including a PLE cell, a heating element, a high-pressure source of an extraction solvent, a pressure regulator, and a cooling coil. The PLE module continuously performs high-pressure, high-temperature extraction on the solid sample to yield liquid sample. The liquid sample is concurrently provided to a purification module including one or more columns. The purification module yields a purified liquid sub-sample containing substantially all of a specific trace substance present in the solid sample. The sub-samples are transferred to a concentrator assembly through a collector inlet. The concentrated sub-sample can be used in subsequent analysis to determine the concentration of the trace substance in the original solid sample.

US Patent:

8062520, Nov 22, 2011

Filed:

Aug 21, 2007

Appl. No.:

11/894743

Inventors:

Hamid Shirkhan - Manchester MA, US

Assignee:

Fluid Management Systems, Inc. - Waltham MA

International Classification:

B01D 11/02

US Classification:

210232, 210450, 422 681, 422261, 422550, 422916

Abstract:

A system for pressurized liquid extraction of solid samples including quick-connect, threadless columns for holding the solid sample is disclosed. A pressurized liquid extraction (PLE) module continuously performs extraction on the solid sample to yield liquid sample. The quick-connect columns include a threadless, cylindrical tube and end cap assemblies, which are structured and arranged to provide a tight interference fit with the inner surface of the annulus of the column portion and with top and bottom cup rings.

US Patent:

60895381, Jul 18, 2000

Filed:

Dec 30, 1998

Appl. No.:

9/224253

Inventors:

Hamid Shirkhan - Newton MA

Assignee:

Fluid Management Systems, Inc. - Waltham MA

International Classification:

F17D 108
F16K 714
F16K 3106

US Classification:

25112917

Abstract:

A valve assembly has a unitary teflon valve housing with six peripheral facets. A recessed area on the surface of each facet forms a valve seat. Pairs of fluid channels formed in the housing each terminate at openings at a central, planar area of a corresponding valve seat. A pair of rigid tubes are disposed in the openings at each valve seat, each tube forming a fluid-tight seal with periphery of the corresponding opening. The tubes extend slightly beyond the surface of the housing by a predetermined clearance. A diaphragm made of a resilient material covers the valve seat. The periphery of the diaphragm is in fluid-tight sealing engagement with the periphery of the valve seat. A central portion of the diaphragm is coupled to a solenoid above the diaphragm. The solenoid moves the diaphragm central portion between a closed position toward the valve seat and an open position away from the valve seat. When in the closed position, the diaphragm central portion sealingly covers the extended ends of the tubes while the predetermined clearance is maintained between the diaphragm and the valve seat to prevent fluid-borne particles from being compressed therebetween.

US Patent:

52385566, Aug 24, 1993

Filed:

May 13, 1992

Appl. No.:

7/882288

Inventors:

Hamid Shirkhan - Dorchester MA

International Classification:

B01D 1508

US Classification:

2101982

Abstract:

The invention provides a separation column useful for liquid-solid column chromatography. In an exemplary embodiment a polytetrafluorethylene tube is provided which is threaded on each end. Threaded polytetrafluorethylene fittings mate with the threads of the tube, and compress an O-ring on each end of the tube, to form a liquid-tight sealing of the tube under pressurized or non-pressurized use. The threaded polytetrafluorethylene tube may be vacuum packed in a plastic bag with a chromatographic medium retained within the polytetrafluorethylene tube. The chromatographic medium may be formed from one or more layers of chromatographic material. Another embodiment incorporates permeable polytetrafluorethylene discs, known generally as frits, in gravity fed polytetrafluorethylene separation column.

US Patent:

48302180, May 16, 1989

Filed:

Jan 27, 1987

Appl. No.:

7/006954

Inventors:

Hamid Shirkhan - Watertown MA

Assignee:

Fluid Management Systems - Watertown MA

International Classification:

B67D 508

US Classification:

222 52

Abstract:

A controlled fluid delivery system comprising a pump and electric drive apparatus which provides precise metering of the fluid, and includes an error correction apparatus by which the system errors may be compensated and calibrated to provide a precisely controlled fluid flow at a continuous speed or small quantities of the fluid by intermittent system operations. Furthermore, the apparatus is modular and may accommodate a variety of mechanical pumps. The controlled fluid delivery system communicates with other apparatus such as measurement devices and process control equipment through standard binary communication lines.