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Geoffrey M Grinstein

age ~78

from New York, NY

Also known as:
  • Grinstein Geoffrey
Phone and address:
115 9Th St, New York, NY 10003
2129959428

Geoffrey Grinstein Phones & Addresses

  • 115 9Th St, New York, NY 10003 • 2129959428 • 2129827774
  • 115 E 9Th St APT 20B, New York, NY 10003 • 9142457453
  • 2837 Sutton St, Yorktown Heights, NY 10598 • 9142457453
  • Yorktown Hts, NY

Us Patents

  • Method And Apparatus For Determining Gene Expression Levels

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  • US Patent:
    6816790, Nov 9, 2004
  • Filed:
    Feb 13, 2003
  • Appl. No.:
    10/365891
  • Inventors:
    Geoffrey Grinstein - New York NY
    Glenn Allen Held - Pelham NY
    Yuhai Tu - Ossining NY
  • Assignee:
    International Business Machines Corporation - Armonk NY
  • International Classification:
    G06F 1900
  • US Classification:
    702 23, 702 19, 702 20, 702 27, 435 6
  • Abstract:
    Techniques for analyzing gene expression levels are provided. In one aspect of the invention, the technique provides a method for determining a concentration level of a target nucleic acid, the target nucleic acid comprising at least one target oligonucleotide. The method determines (i) a measure of affinity value of the target oligonucleotide with a probe oligonucleotide; and (ii) a hybridization intensity value for the target oligonucleotide and the probe oligonucleotide at a probe spot. The measure of affinity value and the hybridization intensity value are used to determine the concentration level of the target nucleic acid.
  • System Employing Dissipative Pseudorandom Dynamics And Selective Feedback For Communications And Measurement

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  • US Patent:
    55793371, Nov 26, 1996
  • Filed:
    Jun 19, 1995
  • Appl. No.:
    8/491624
  • Inventors:
    Geoffrey Grinstein - Yorktown Heights NY
    Neil Gershenfeld - Somerville MA
  • Assignee:
    International Business Machines Corporation - Armonk NY
  • International Classification:
    H04B 1500
  • US Classification:
    375206
  • Abstract:
    A communication and/or measurement system includes a transmitter that modulates a pseudo-random noise signal with a message signal to produce a wideband signal for transmission. A receiver, which demodulates the wideband signal to recover the message signal, includes an "analog" feedback shift register that reproduces the noise signal based on samples of the received signal. The AFSR is characterized by a function that agrees with the function that characterizes the LFSR, at the points at which that function is defined. Further, the AFSR characterizing function has stable fixed points at these values, i. e. , it has a slope of less than one in these regions. Specifically, the AFSR's function has stable fixed points at integer values and unstable fixed points at half-integer values and, the stable fixed points act as attractors. The AFSR thus produces a sequence that relaxes to the nearest integer-valued sequence. In one embodiment in which signal values that represent binary values are -1 and +1, the coupling circuitry compares the quantity. vertline. (. vertline. S. sub. n. vertline. -1). vertline.
  • System Employing Continuous-Time Dissipative Pseudorandom Dynamics For Communications And Measurement

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  • US Patent:
    57373604, Apr 7, 1998
  • Filed:
    Jun 19, 1995
  • Appl. No.:
    8/492285
  • Inventors:
    Geoffrey Grinstein - Yorktown Heights NY
    Neil Gershenfeld - Somerville MA
  • Assignee:
    International Business Machines, Corp. - Armonk NY
  • International Classification:
    H04B 1500
    H04K 100
    H04L 2730
  • US Classification:
    375206
  • Abstract:
    A communication and/or measurement system includes in a a transmitter an analog feedback system that modulates a pseudo-random noise signal with a message signal to produce a wideband signal for transmission. A receiver, which demodulates the wideband signal to recover the message signal, includes an associated analog feedback system that reproduces the noise signal based on the received signal. The analog feedback systems (AFS) are continuous-time generalizations of a linear feedback shift register ("LFSR"). The AFS are characterized by a function that agrees with the function that characterizes the LFSR, at the points at which that function is defined. Further, the AFS characterizing function has stable periodic orbits at these values, and the stable periodic orbits are attractors. The AFS thus produces a signal that relaxes on to a nearest periodic orbit that generalizes to continuous time the maximal sequence produced by the corresponding LFSR. The AFS in the transmitter, which operates in accordance with a harmonic oscillator, is characterized by the following differential equation: ##EQU1## where the. alpha. sub.

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