Frederick Dewey - Redwood City CA, US Euan Ashley - Menlo Park CA, US Carlos Daniel Bustamante - Emerald Hills CA, US Atul Butte - Menlo Park CA, US Jake Byrnes - San Francisco CA, US Rong Chen - Fremont CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G06F 19/12
US Classification:
702 19
Abstract:
An embodiment of the present invention is a methodology for prioritizing variants relevant to inherited Mendelian (“single gene”) disease syndromes according to disease phenotype, gene, and variant level information.
Phased Whole Genome Genetic Risk In A Family Quartet
Frederick Dewey - Redwood City CA, US Euan A. Ashley - Menlo Park CA, US Matthew Wheeler - Sunnyvale CA, US Sergio Cordero - East Palo Alto CA, US Colleen Caleshu - San Mateo CA, US Kelly Ormond - Redwood City CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G06N 5/02
US Classification:
706 46
Abstract:
An embodiment of the present invention is a method for resolving long-range haplotype phase based on family pedigree data, inheritance state determination, and population linkage disequilibrium data. A method according to an embodiment of the present invention provides for the evaluation of genome wide risk using phased haplotype data.
Method And System For Network Modeling To Enlarge The Search Space Of Candidate Genes For Diseases
Frederick E. Dewey - Redwood City CA, US Euan A. Ashley - Menlo Park CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G06F 19/12
US Classification:
703 11
Abstract:
With the advent of low cost, high-throughput whole genome sequencing (“next generation sequencing”), tools are available to assay human genetic variation contributing to inherited disease syndromes. A method is disclosed for prioritization of genetic variants, and identification of disease genes, using network modeling of gene associations.
Phased Whole Genome Genetic Risk In A Family Quartet
Frederick Dewey - Redwood City CA, US Euan Ashley - Menlo Park CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
G06F 19/24 G06F 19/18
US Classification:
702 20
Abstract:
In an embodiment of the present invention, three novel human reference genome sequences were developed based on the most common population-specific DNA sequence (“major allele”). Methods were developed for their integration into interpretation pipelines for highthroughput whole genome sequencing.
Medicine Doctors
Dr. Frederick E Dewey, Stanford CA - MD (Doctor of Medicine)
John Frederick Dewey (born 1937) is a British structural geologist and a strong proponent of the theory of Plate Tectonics, building upon the early work ...
Name / Title
Company / Classification
Phones & Addresses
Frederick William Dewey
HADLOCK BAND, INCORPORATED
PO Box 179, Ionia, NY 14475 1170 Strong Rd, Victor, NY 14564
Frederick W. Dewey President
Kachingle Internet · Nonclassifiable Establishments · Business Services at Non-Commercial Site · Finacial Services Business Services at Non-Commercial Site
PO Box 1559, Mountain View, CA 94042 715 Charleston Ct, Palo Alto, CA 94303
In the past few years, the cost of whole-genome sequencing has fallen to the point where it could soon be feasible to use it in everyday health care, said Dr. Frederick Dewey of Stanford University, the lead researcher on the new study. Based on his teams findings, Dewey said, A lot more work is
Date: Jun 20, 2014
Category: Health
Source: Google
It Takes 100 Hours to Analyze a Human Genome for Disease
The gist of it is we found that the results are generally not clinically acceptable, said Frederick Dewey, lead author of the analysis, published in the Journal of the American Medical Association. Its a relatively sobering thought, and there are tough hurdles to get over before this is common.
Date: Mar 12, 2014
Category: Health
Source: Google
Study of the Day: Family DNA Test Changes Disease-Risk Analysis
METHODOLOGY: Stanford University School of Medicine led by Frederick Dewey analyzed DNA samples from the four-person West family that included a whole-genome interpretation of medical risks, a first in genetic research. The researchers also created new ethnically matched reference genomes against wh