Fabrice Gilbert Simeon
age ~53
from Kensington, MD
- Also known as:
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- Fabrice G Simeon
Fabrice Simeon Phones & Addresses
- Kensington, MD
- Rehoboth Beach, DE
- Washington, DC
- Rome, OH
- 3001 Veazey Ter NW APT 1003, Washington, DC 20008
Work
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Position:Clerical/White Collar
Education
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Degree:High school graduate or higher
Us Patents
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2-Fluorothiazole Derivatives Useful As Imaging Agents; Methods Of Synthesis, And Methods Of Use
view source -
US Patent:20110098326, Apr 28, 2011
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Filed:Oct 26, 2009
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Appl. No.:12/605467
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Inventors:Victor W. Pike - Bethesda MD, US
Fabrice G. Simeon - Washington DC, US -
International Classification:A61K 31/426
C07D 277/32
G01N 33/53
A61P 25/28
A61P 25/30
A61P 25/24
A61P 25/22 -
US Classification:514365, 548202, 548203, 435 722
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Abstract:Novel F-labeled thiazole derivatives useful for imaging of metabotropic glutamate subtype 5 receptors (mGluR5) in living mammalian brain are disclosed herein. Also disclosed herein is a synthetic method for making the claimed thiazole derivatives under thermal heating or microwave conditions for aryl thioethers that provides the compounds in high yield. Imaging methods in which the claimed F-labeled thiazole derivatives are used as imaging agents are also disclosed. Halogen substituted thiazole derivative disclosed herein are also useful as therapeutic agents. Methods of treating mGluR5 mediated disorders with certain halogen substituted thiazole derivatives are disclosed.
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Fabrice Simeon
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