Elizabeth F Illyes

US Patent:

20030018049, Jan 23, 2003

Filed:

Aug 22, 2002

Appl. No.:

10/226994

Inventors:

Dennis Godek - Glastonbury CT, US
Richard Darrington - Uncasville CT, US
Elizabeth Illyes - Marshall IL, US

International Classification:

A61K031/55
A61K031/445
A61K031/40
A61K031/7048

US Classification:

514/317000, 514/217120, 514/426000, 514/029000

Abstract:

The invention is directed to a method of treating cancer or a bacterial or protozoal infection in a mammalian subject in need of such treatment. The method comprises the adjunctive administration of pharmaceutically effective amounts of a macrolide antibiotic and a Substance P antagonist. The invention also encompasses a method of preventing or treating emesis associated with macrolide antibiotic administration. The invention further encompasses novel compositions comprising a macrolide antibiotic and a Substance P antagonist.

US Patent:

20040063649, Apr 1, 2004

Filed:

Sep 18, 2003

Appl. No.:

10/666908

Inventors:

Dennis Godek - Glastonbury CT, US
Richard Darrington - Uncasville CT, US
Elizabeth Illyes - Marshall IL, US

Assignee:

Pfizer Inc

International Classification:

A61K031/7048
A61K031/55
A61K031/445
A61K031/40

US Classification:

514/029000, 514/317000, 514/408000, 514/217120

Abstract:

The invention is directed to a method of treating cancer or a bacterial or protozoal infection in a mammalian subject in need of such treatment. The method comprises the adjunctive administration of pharmaceutically effective amounts of a macrolide antibiotic and a Substance P antagonist. The invention also encompasses a method of preventing or treating emesis associated with macrolide antibiotic administration. The invention further encompasses novel compositions comprising a macrolide antibiotic and a Substance P antagonist.

US Patent:

20020016301, Feb 7, 2002

Filed:

Aug 15, 2001

Appl. No.:

09/929899

Inventors:

Dennis Godek - Glastonbury CT, US
Richard Darrington - Uncasville CT, US
Elizabeth Illyes - Marshall IL, US

International Classification:

A61K031/7048
A61K031/445

US Classification:

514/028000, 514/317000

Abstract:

The invention is directed to a method of treating cancer or a bacterial or protozoal infection in a mammalian subject in need of such treatment. The method comprises the adjunctive administration of pharmaceutically effective amounts of a macrolide antibiotic and a Substance P antagonist. The invention also encompasses a method of preventing or treating emesis associated with macrolide antibiotic administration. The invention further encompasses novel compositions comprising a macrolide antibiotic and a Substance P antagonist.