Deepak Dalvie - San Diego CA, US Roger Ruggeri - San Diego CA, US
International Classification:
A61K 31/4706 C07D 215/38
US Classification:
514313000, 546159000
Abstract:
Compounds resulting from the administration of torcetrapib to a mammal, and the use of such compounds as an indicator or biomarker to the presence or exposure of torcetrapib in the plasma of a mammal including humans. The invention is also directed to cholesteryl ester transfer protein (CETP) inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein (HDL)-cholesterol and to lower certain other plasma lipid levels, such as low density lipoprotein (LDL)-cholesterol and triglycerides.
Cereblon Binding Compounds, Compositions Thereof, And Methods Of Treatment Therewith
- Summit NJ, US Matthew D. Correa - San Diego CA, US Deepak Dalvie - Carlsbad CA, US Virginia Heather Sharron Grant - San Diego CA, US Joshua Hansen - La Jolla CA, US Evan J. Horn - San Diego CA, US Dehua Huang - San Diego CA, US Christopher Mayne - Boulder CO, US Stephen Norris - San Diego CA, US John J. Sapienza - Chula Vista CA, US Lida Tehrani - San Diego CA, US Brandon W. Whitefield - San Diego CA, US
International Classification:
C07D 401/14
Abstract:
Provided herein are piperidine dione compounds having the following structure:
Cereblon Binding Compounds, Compositions Thereof, And Methods Of Treatment Therewith
- Summit NJ, US Matthew D. Correa - San Diego CA, US Deepak Dalvie - Carlsbad CA, US Virginia Heather Sharron Grant - San Diego CA, US Joshua Hansen - La Jolla CA, US Evan J. Horn - San Diego CA, US Dehua Huang - San Diego CA, US Christopher Mayne - Boulder CO, US Stephen Norris - San Diego CA, US John J. Sapienza - Chula Vista CA, US Lida Tehrani - San Diego CA, US Brandon W. Whitefield - San Diego CA, US
International Classification:
C07D 401/14 A61P 35/00
Abstract:
Provided herein are piperidine dione compounds having the following structure:
Sphingosine 1 Phosphate Receptor Agonists For Neuroprotection
- Couvet, CH Brett Skolnick - San Diego CA, US Deepak Dalvie - Carlsbad CA, US
International Classification:
A61K 31/4245
Abstract:
Methods of treating conditions for which S1P-mediated neuroprotection is medically indicated, comprising administering to a subject in need thereof an agonist of the sphingosine 1-phosphate receptor (S1P receptor); such as a compound having the following structure (See Formula 1): or a pharmaceutically acceptable salt, stereoisomer, homolog, hydrate or solvate thereof.
Pfizer Global Research and Development since 2004
Research Fellow, Pharmacokinetics, Dynamics and Metabolism
Pfizer Global Research and Development 2001 - 2004
Associate Research Fellow, Pharmacokinetics, Dynamics and Metabolism
Pfizer Global Research and Development 1998 - 2001
Sr. Research Investigator, Pharmacokinetics, Dynamics and Metabolism
Pfizer Global Research and Development 1995 - 1998
Sr. Research Scientist, Pharmacokinetics, Dynamics and Metabolism
Pfizer Global Research and Development Oct 1992 - 1995
Research Scientist, Drug Metabolism and Pharmacokinetics
Education:
State University of New York at Buffalo 1984 - 1989
Ph.D., Medicinal Chemistry
University Department of Chemical Technology (ICT), University of Mumbai 1982 - 1984
M.Sc. (Tech), Technology of Pharmaceuticals and Fine Chemicals
University Department of Chemical Technology (ICT), University of Mumbai 1979 - 1982
BSc (Tech), Technology of Pharmaceuticals and Fine chemicals
University of Mumbai 1977 - 1979
B. Sc. (Hons), Chemistry
Skills:
Development Research Metabolism Global Research Microsoft Dynamics Pharmacokinetics