Deborah A Buonagurio

US Patent:

7485415, Feb 3, 2009

Filed:

Feb 19, 2003

Appl. No.:

10/505818

Inventors:

Deborah A. Buonagurio - Rye NY, US
Alice F. Georgiu - Montgomery NY, US
Robert A. Lerch - New Hempstead NY, US
Bruce B. Mason - Downington PA, US
Shridhara C. Murthy - Ann Arbor MI, US
Ruth S. Rappaport - Strafford PA, US
Mohinder S. Sidhu - New City NY, US
Stephen A. Udem - New York NY, US
Timothy J. Zamb - Nyack NJ, US

Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC

International Classification:

C12Q 1/70
C12N 15/46
C12N 15/63
C12N 1/21
C12N 5/10
A61K 39/15

US Classification:

435 5, 4353201, 435 693, 435325, 4352523, 43525411, 4242151

Abstract:

Isolated nucleic acid molecules comprising a gene segment from a rhesus rotavirus (RRV) or from one of three rhesus: human reassortant viruses are disclosed, including isolated nucleic acid molecules having a sequence selected from the group consisting of: SEQ ID NO: 1-14, inclusive, and isolated nucleic acid molecules encoding a protein having a sequence selected from the group consisting of SEQ ID NO: 15-28, inclusive, as well as variants of the isolated nucleic acid molecules.

US Patent:

20090246829, Oct 1, 2009

Filed:

Feb 3, 2009

Appl. No.:

12/365122

Inventors:

Deborah A. Buonagurio - Rye NY, US
Alice F. Georgiu - Montgomery NY, US
Robert A. Lerch - New Hempstead NY, US
Bruce B. Mason - Downington PA, US
Shridhara C. Murthy - Ann Arbor MI, US
Ruth S. Rappaport - Strafford PA, US
Mohinder S. Sidhu - New City NY, US
Stephen A. Udem - New York NY, US
Timothy J. Zamb - Nyack NJ, US

Assignee:

Services - Rockville MD

International Classification:

C12P 21/02
C12N 15/11
C12N 15/00
C12N 1/21
C12N 5/00
C12N 1/19
C12N 5/06

US Classification:

435 691, 536 2372, 4353201, 43525233, 435348, 4352542, 435358, 435365

Abstract:

Isolated nucleic acid molecules comprising a gene segment from a rhesus rotavirus (RRV) or from one of three rhesus:human reassortant viruses are disclosed, including isolated nucleic acid molecules having a sequence selected from the group consisting of: SEQ ID NO: 1-14, inclusive, and isolated nucleic acid molecules encoding a protein having a sequence selected from the group consisting of SEQ ID NO: 15-28, inclusive, as well as variants of the isolated nucleic acid molecules.

US Patent:

56937555, Dec 2, 1997

Filed:

Oct 21, 1994

Appl. No.:

8/327129

Inventors:

Deborah Anne Buonagurio - Mamaroneck NY
Mathew Longiaru - West Orange NJ

Assignee:

Hoffmann-La Roche Inc. - Nutley NJ

International Classification:

C07K 100
C12Q 170
C12P 2106
C12N 120

US Classification:

530350

Abstract:

A synthetic gene which codes for at least one epitope from the immunodominant conserved region of HTLV-I env. gp 21 as well as hybrid genes utilizing the synthetic gene in conjunction with other epitopes from HTLV-Ienv. gp 46 and gp 21; the corresponding gene products, recombinant vectors containing the genes, methods for producing the polypeptides and methods for detecting antibodies to HTLV-I using the polypeptides of the invention.

US Patent:

58378189, Nov 17, 1998

Filed:

Aug 2, 1996

Appl. No.:

8/691989

Inventors:

Deborah A. Buonagurio - Mamaroneck NY
Mathew Longiaru - West Orange NJ

Assignee:

Roche Diagnostic Systems, Inc. - Branchburg NJ

International Classification:

C07K 1416
C12P 2102
C12N 700
A61K 3921

US Classification:

530350

Abstract:

A synthetic gene which codes for at least one epitope from the immunodominant conserved region of HTLV-I env. gp 21 as well as hybrid genes utilizing the synthetic gene in conjunction with other epitopes from HTLV-Ienv. gp 46 and gp 21; the corresponding gene products, recombinant vectors containing the genes, methods for producing the polypeptides and methods for detecting antibodies to HTLV-I using the polypeptides of the invention.