David A Eiznhamer

US Patent:

7250437, Jul 31, 2007

Filed:

Dec 29, 2004

Appl. No.:

11/024615

Inventors:

David E. Zembower - La Grange IL, US
David A. Eiznhamer - Bloomingdale IL, US

Assignee:

Angion Biomedica Corp. - Garden City NY

International Classification:

A61K 31/415
A61K 31/4155
C07D 231/12

US Classification:

514408, 5483731

Abstract:

The present invention provides compounds having formula (I):.

US Patent:

7265112, Sep 4, 2007

Filed:

Dec 29, 2004

Appl. No.:

11/025373

Inventors:

David E. Zembower - La Grange IL, US
David A. Eiznhamer - Bloomingdale IL, US

Assignee:

Angion Biomedica Corp. - Garden City NJ

International Classification:

A61K 31/4155
A61K 31/5377
C07D 231/12
C07D 413/14

US Classification:

5142355, 514406, 544124, 5483657

Abstract:

The present invention provides compounds having formula (I):.

US Patent:

8580834, Nov 12, 2013

Filed:

Aug 13, 2007

Appl. No.:

11/891618

Inventors:

David E. Zembower - La Grange IL, US
David A. Eiznhamer - Bloomingdale IL, US

Assignee:

Angion Biomedica Corp. - Garden City NY

International Classification:

A61K 31/4155
A61K 31/341
C07D 231/12
C07D 307/52

US Classification:

514406, 514461, 5483657, 549472

Abstract:

The present invention provides compounds having formula (I):.

US Patent:

20040019022, Jan 29, 2004

Filed:

Jul 18, 2003

Appl. No.:

10/622302

Inventors:

Karen Stec - Barrington IL, US
Israel Rubinstein - Highland Park IL, US
David Eiznhamer - Bloomingdale IL, US
Michael Flavin - Darien IL, US

International Classification:

A61K038/12
A61K038/00
A61K038/16
A61K031/704
A61K031/60
A61K031/496

US Classification:

514/159000, 514/008000, 514/192000, 514/034000, 514/252130, 514/029000, 514/002000, 514/253080, 514/312000

Abstract:

A method for treating cellular and tissue damage is disclosed. The inventive method comprises the use of 2,3-alkylcarbonyloxybenzoic acid and salts thereof in the prevention and treatment of dysfunction, damage, and/or injuries to organs, tissues and/or cells in human or animal subjects caused by diseases, infections and conditions such as pneumonia, coronavirus, multiple transfusions, trauma, ischemic-reperfusion dysfunctions, stroke, drug overdose, and severe acute respiratory syndrome. The 2,3-alkylcarbonyloxybenzoic acid may be used alone or in combination with other therapeutic agents such as antibiotics. The acid may be administered in any practical delivery form, and in free acid or buffered form.

US Patent:

20040180882, Sep 16, 2004

Filed:

Dec 18, 2003

Appl. No.:

10/740708

Inventors:

David Zembower - La Grange IL, US
David Eiznhamer - Bloomingdale IL, US

International Classification:

C07D417/02
C07D413/02
C 07D 4 3/02

US Classification:

514/227500, 514/235500, 514/326000, 514/254050, 514/406000, 544/060000, 544/140000, 544/371000, 546/211000, 548/364100, 548/373100

Abstract:

The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R, Rand B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.

US Patent:

20070232577, Oct 4, 2007

Filed:

Mar 23, 2007

Appl. No.:

11/728284

Inventors:

Ze-Qi Xu - Woodridge IL, US
Ali Koohang - Plainfield IL, US
Aye Aye Mar - Tinley Park IL, US
Nathan Majewski - Bryn Mawr PA, US
David Eiznhamer - Bloomingdale IL, US
Michael Flavin - Darien IL, US

Assignee:

Advanced Life Sciences, Inc. - Woodridge IL

International Classification:

A61K 31/58
A61K 31/56
C07J 53/00

US Classification:

514169000, 514176000, 540047000, 552511000

Abstract:

The present invention comprises small molecule inhibitors of cell proliferative conditions, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprising pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.

US Patent:

20090062243, Mar 5, 2009

Filed:

Jul 10, 2008

Appl. No.:

12/171069

Inventors:

Ali Koohang - Plainfield IL, US
Aye Aye Mar - Tinley Park IL, US
Erika Szotek - Hanover Park IL, US
Ze-Qi Xu - Woodridge IL, US
David A. Eiznhamer - Bloomingdale IL, US
Michael T. Flavin - Darien IL, US

Assignee:

ADVANCED LIFE SCIENCES, INC. - Woodridge IL

International Classification:

A61K 31/56
C07J 53/00
A61P 35/04
A61P 29/00
C12N 5/06

US Classification:

514169, 552511, 435375, 514177

Abstract:

The present invention comprises lupine-type triterpenoids that inhibit cell proliferations, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprising pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.

US Patent:

20100144688, Jun 10, 2010

Filed:

Dec 9, 2009

Appl. No.:

12/634305

Inventors:

Ali Koohang - Plainfield IL, US
Aye Aye Mar - Tinley Park IL, US
Erika Szotek - Hanover Park IL, US
Ze-Qi Xu - Woodridge IL, US
David A. Eiznhamer - Bloomingdale IL, US
Michael T. Flavin - Darien IL, US

Assignee:

ADVANCED LIFE SCIENCES, INC. - Woodridge IL

International Classification:

A61K 31/568
C07J 53/00
C07J 17/00
C07J 1/00
A61K 31/58
A61P 31/12
A61P 35/00

US Classification:

514172, 552510, 549416, 514169

Abstract:

The present invention comprises small molecule inhibitors of cell proliferative conditions, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprises pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.