Daryll A Emery

US Patent:

6432412, Aug 13, 2002

Filed:

Jul 26, 1999

Appl. No.:

09/361081

Inventors:

Daryll A. Emery - Willmar MN
Darren E. Straub - Willmar MN
Richard Huisinga - Willmar MN
Beth A. Carlson - Murdock MN

Assignee:

Willmar Poultry Company, Inc. - Willmar MN

International Classification:

A61K 3902

US Classification:

4242411, 4242341, 4241841, 4242031, 4242821, 4242571, 424823, 424826, 514 2, 530350, 530825

Abstract:

The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.

US Patent:

6682754, Jan 27, 2004

Filed:

Nov 24, 1999

Appl. No.:

09/449271

Inventors:

Daryll A. Emery - New London MN
Darren E. Straub - New London MN

Assignee:

Willmar Poultry Company, Inc. - Willmar MN

International Classification:

A61F 200

US Classification:

424426, 424425, 424423, 424422, 424489, 424490, 424484, 424494, 4241841, 42419517, 1065011

Abstract:

The disclosure provides a method for administering an agent to an avian species by in ovo delivery of an implant releasably containing the agent. In one embodiment, the method is particularly advantageous for stimulating an immune response in a bird by in ovo administration of a biocompatible implant releasably containing an immunogen. The implant can provide for sustained or delayed release of the immunogen or both. The amount of immunogen that is released from the implant into the bird is preferably sufficient to effectively stimulate a primary immune response to the immunogen. Other agents which can be administered according to the method of the invention are disclosed.

US Patent:

7138124, Nov 21, 2006

Filed:

Jun 3, 2003

Appl. No.:

10/454305

Inventors:

Daryll A. Emery - New London MN, US
Darren E. Straub - New London MN, US
Donavan E. Zammert - Willmar MN, US
Gayla K. Kallevig - Willmar MN, US

Assignee:

Epitopix, LLC - Willmar MN

International Classification:

A61K 39/02
A61K 39/108
A61K 39/102
A61K 39/00
A61K 39/38
A61K 39/116
A61K 38/00

US Classification:

4242341, 4241841, 4242031, 4242361, 4242411, 4242571, 4242581, 4242551, 424823, 424824, 424825, 424826, 424827, 424828, 424829, 514 2, 514 12

Abstract:

The present invention provides compositions including at least two siderophore receptor polypeptides and at least two porins from a gram negative microbe, and preferably, lipopolysaccharide at a concentration of no greater than about 10. 0 endotoxin units per milliliter. The present invention also provides methods of makino and methods of using such compositions.

US Patent:

7138125, Nov 21, 2006

Filed:

Apr 22, 2004

Appl. No.:

10/830258

Inventors:

Daryll A. Emery - New London MN, US
Darren E. Straub - New London MN, US

Assignee:

Epitopix LLC - Willmar MN

International Classification:

A61K 39/00
A61K 38/00
A61K 39/09
A61K 39/116
A61K 39/108
A61K 39/38
A61K 37/18

US Classification:

4242341, 4241841, 4242441, 4242031, 4242411, 4242571, 4242581, 424823, 514 2, 514 12

Abstract:

The present invention provides methods for treating an animal for low milk production. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10. 0 endotoxin units per milliliter.

US Patent:

7147857, Dec 12, 2006

Filed:

Jun 3, 2003

Appl. No.:

10/454306

Inventors:

Daryll A. Emery - New London MN, US
Darren E. Straub - New London MN, US

Assignee:

Epitopix, LLC - Willmar MN

International Classification:

A61K 39/00
A61K 38/00
A61K 39/09
A61K 39/116
A61K 39/108
A01N 37/18

US Classification:

4241841, 4242441, 4242341, 4242031, 4242411, 4242571, 4242581, 424823, 514 2, 514 12

Abstract:

The present invention provides methods for treating an animal having a high somatic cell count. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10. 0 endotoxin units per milliliter.

US Patent:

7160549, Jan 9, 2007

Filed:

Apr 22, 2004

Appl. No.:

10/829775

Inventors:

Daryll A. Emery - New London MN, US
Darren E. Straub - New London MN, US
Donavan E. Zammert - Willmar MN, US
Gayla K. Kallevig - Willmar MN, US

Assignee:

Epitopix, LLC - Willmar MN

International Classification:

A61K 39/02
A61K 39/108
A61K 45/00
C12N 7/02
C07K 14/00
C07K 16/00
C07K 17/00

US Classification:

4242341, 4242031, 4242361, 4242411, 4242571, 4242581, 4242551, 4242561, 4242591, 4242821, 4242601, 4242611, 435239, 530344, 530412

Abstract:

The present invention provides methods for making compositions including siderophore receptor polypeptides and porins from gram negative microbes. The methods include providing a gram negative microbe, disrupting the microbe, solubilizing the disrupted microbe, and isolating the polypeptides.

US Patent:

7341732, Mar 11, 2008

Filed:

Apr 22, 2004

Appl. No.:

10/829838

Inventors:

Daryll A. Emery - New London MN, US
Darren E. Straub - New London MN, US

Assignee:

Epitopix, LLC - Willmar MN

International Classification:

A61K 39/108
A61K 39/00
A61K 39/38
A61K 39/116
A61K 38/00
A61K 39/112
A01N 37/18

US Classification:

4242341, 4241841, 4242411, 4242551, 4242571, 4242581, 4242591, 4242601, 424203, 424823, 514 2, 514 12

Abstract:

The present invention provides methods for treating mastitis in a milk producing animal. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10. 0 endotoxin units per milliliter.

US Patent:

7371393, May 13, 2008

Filed:

Mar 22, 2006

Appl. No.:

11/386393

Inventors:

Daryll A. Emery - New London MN, US
Darren E. Straub - New London MN, US

Assignee:

Epitopix, LLC - Willmar MN

International Classification:

A61K 39/108
A61K 39/00
A61K 39/38
A61K 39/116
A61K 38/00
A61K 39/112
A01N 37/18

US Classification:

4242341, 4241841, 4242411, 4242551, 4242571, 4242581, 4242591, 4242601, 424203, 424823, 514 2, 514 12

Abstract:

The present invention provides methods for reducing shedding in an animal. Generally, the method includes administcriirn to an animal a composition including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10. 0 endotoxin units per milliliter.