Cynthia J Schroedel

US Patent:

43992226, Aug 16, 1983

Filed:

Aug 6, 1979

Appl. No.:

6/064321

Inventors:

Song H. Bok - Decatur IL
LeRoy E. Jackson - Ogden UT
Cynthia J. Schroedel - Brookfield IL
Martin Seidman - Decatur IL

Assignee:

A. E. Staley Manufacturing Company - Decatur IL

International Classification:

C12N 992
C12P 1924
C12P 1914
C12R 1465

US Classification:

435234

Abstract:

Acidophilic and acidoduric streptomycetes strains have been found to produce carbohydrases. These Streptomyces effectively elaborate glucose isomerase under acid conditions typically unfavorable for growth of conventional glucose isomerase producing Streptomyces. Sterilization of the culture and production media may be avoided by selectively propagating newly discovered Streptomyces acidodurans under acidic conditions which will effectively eliminate contaminating microorganisms. The Streptomyces acidodurans herein also have the ability to undergo cultivation and elaborate glucose isomerase over a relatively broad pH range. Constitutive streptomycetes strains have also been isolated. Glucose isomerases derived from these Streptomyces strains are particularly effective for isomerizing glucose syrups to fructose-containing syrups.

US Patent:

44593546, Jul 10, 1984

Filed:

Oct 1, 1982

Appl. No.:

6/432173

Inventors:

Song H. Bok - Decatur IL
LeRoy E. Jackson - Ogden UT
Cynthia J. Schroedel - Brookfield IL
Martin Seidman - Decatur IL

Assignee:

A. E. Staley Manufacturing Company - Decatur IL

International Classification:

C12P 1924
C12N 992

US Classification:

435 94

Abstract:

Acidophilic and acidoduric streptomycetes strains have been found to produce carbohydrases. These Streptomyces effectively elaborate glucose isomerase under acid conditions typically unfavorable for growth of conventional glucose isomerase producing Streptomyces. Sterilization of the culture and production media may be avoided by selectively propagating newly discovered Streptomyces acidodurans under acidic conditions which will effectively eliminate contaminating micro-organisms. The Streptomyces acidodurans herein also have the ability to undergo cultivation and elaborate glucose isomerase over a relatively broad pH range. Constitutive streptomycetes strains have also been isolated. Glucose isomerases derived from these Streptomyces strains are particularly effective for isomerizing glucose syrups to fructose-containing syrups.