Cynthia A Briscoe

US Patent:

6527890, Mar 4, 2003

Filed:

Dec 9, 1999

Appl. No.:

09/460283

Inventors:

Cynthia G. Briscoe - Tempe AZ
Huinan Yu - Chandler AZ
Piotr Grodzinski - Chandler AZ
Rong-Fong Huang - Tempe AZ
Jeremy W. Burdon - Scottsdale AZ

Assignee:

Motorola, Inc. - Schaumburg IL

International Classification:

B32B 3126

US Classification:

156 8911, 156 8912, 96101

Abstract:

A micro-gas chromatograph column is formed by texturing a channel into a plurality of green-sheet layers, which are then sintered together to form a substantially monolithic structure. A thick-film paste may be added to the channel textured in the green-sheet layers to provide a porous plug sintered in the micro-gas chromatograph column in the substantially monolithic. A thermal conductivity detector is formed in the substantially monolithic structure by depositing a conductive thick-film paste on the surface of one of the green-sheet layers to define a resistor in an exit channel of the micro-gas chromatograph column.

US Patent:

6544734, Apr 8, 2003

Filed:

Dec 9, 1999

Appl. No.:

09/460281

Inventors:

Cynthia G. Briscoe - Tempe AZ 85284
Huinan Yu - Chandler AZ 85226
Piotr Grodzinski - Chandler AZ 85224
Robert Marrero - Chandler AZ 85226
Jeremy W. Burdon - Scottsdale AZ 85259
Rong-Fong Huang - Tempe AZ 85284

International Classification:

C12Q 168

US Classification:

435 6, 435 911, 435 793, 536 2532, 536 254

Abstract:

A multilayered microfluidic DNA analysis system includes a cell lysis chamber, a DNA separation chamber, a DNA amplification chamber, and a DNA detection system. The multilayered microfluidic DNA analysis system is provided as a substantially monolithic structure formed from a plurality of green-sheet layers sintered together. The substantially monolithic structure has defined therein a means for heating the DNA amplification chamber and a means for cooling the DNA amplification chamber. The means for heating and means for cooling operate to cycle the temperature of the DNA amplification chamber as required for performing a DNA amplification process, such as PCR.

US Patent:

6592733, Jul 15, 2003

Filed:

Nov 12, 1999

Appl. No.:

09/438873

Inventors:

Barbara Foley - Phoenix AZ
Jaymie Sawyer - Chandler AZ
Cynthia G. Briscoe - Tempe AZ

Assignee:

Motorola, Inc. - Schaumburg IL

International Classification:

G01N 2726

US Classification:

204603, 204452, 250573, 2504581, 356344

Abstract:

A capillary electrophoresis device having a substrate layer and a cover layer, with a plurality of electrophoresis channels formed in the substrate layer, includes an optical waveguide system that transmits excitation radiation from a source port into each one of the electrophoresis channels. The optical waveguide system is defined by regions, within either the cover or substrate, that have an index of refraction higher than that of the surrounding material.

US Patent:

6732567, May 11, 2004

Filed:

Dec 5, 2002

Appl. No.:

10/310378

Inventors:

Cynthia G. Briscoe - Tempe AZ
Huinan Yu - Chandler AZ
Piotr Grodzinski - Chandler AZ
Rong-Fong Huang - Tempe AZ
Jeremy W. Burdon - Scottsdale AZ

Assignee:

Motorola, Inc. - Schaumburg IL

International Classification:

G01N 3002

US Classification:

73 2339, 73 2335, 73 232, 96101

Abstract:

A micro-gas chromatograph column is formed by texturing a channel into a plurality of green-sheet layers, which are then sintered together to form a substantially monolithic structure. A thick-film paste may be added to the channel textured in the green-sheet layers to provide a porous plug sintered in the micro-gas chromatograph column in the substantially monolithic. A thermal conductivity detector is formed in the substantially monolithic structure by depositing a conductive thick-film paste on the surface of one of the green-sheet layers to define a resistor in an exit channel of the micro-gas chromatograph column.

US Patent:

6984516, Jan 10, 2006

Filed:

Jan 10, 2003

Appl. No.:

10/340057

Inventors:

Cynthia G. Briscoe - Tempe AZ, US
Huinan Yu - Chandler AZ, US
Piotr Grodzinski - Chandler AZ, US
Robert Marrero - Chandler AZ, US
Jeremy W. Burdon - Scottsdale AZ, US
Rong-Fong Huang - Tempe AZ, US

Assignee:

Motorola, Inc. - Schaumburg IL

International Classification:

C12M 1/34
C12P 19/34
B01J 19/08

US Classification:

4352872, 435 911, 435 912, 42218629

Abstract:

A multilayered microfluidic DNA analysis system includes a cell lysis chamber, a DNA separation chamber, a DNA amplification chamber, and a DNA detection system. The multilayered microfluidic DNA analysis system is provided as a substantially monolithic structure formed from a plurality of green-sheet layers sintered together. The substantially monolithic structure has defined therein a means for heating the DNA amplification chamber and a means for cooling the DNA amplification chamber. The means for heating and means for cooling operate to cycle the temperature of the DNA amplification chamber as required for performing a DNA amplification process, such as PCR.

US Patent:

20040043479, Mar 4, 2004

Filed:

Nov 14, 2002

Appl. No.:

10/149318

Inventors:

Cynthia Briscoe - Tempe AZ, US
Jeremy Burdon - Scottsdale AZ, US
Tony Chan - Scottsdale AZ, US
Barbara Barenburg - Phoenix AZ, US
Piotr Grodzinski - Chandler AZ, US
George Hawkins - Gilbert AZ, US
Rong-Fong Huang - Fremont CA, US
Peter Kahn - Phoenix AZ, US
Robert Marcero - Chandler AZ, US
Mark McGarry - San Diego CA, US
Todd Tuggle - Oceanside CA, US
Huinan Yu - Buffalo Grove IL, US

International Classification:

C12M001/34

US Classification:

435/288500, 435/287200

Abstract:

The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices. In preferred aspects, the devices are fabricated using ceramic multilayer technology to form devices in which parallel, independently controlled molecular reactions, such as nucleic acid amplification reactions including the polymerase chain reaction (PCR) can be performed. Additionally, the devices can include and comprise micro-gas chromatographs similarly fabricated from ceramics.

US Patent:

20110197655, Aug 18, 2011

Filed:

Dec 7, 2010

Appl. No.:

12/962376

Inventors:

Cynthia G. Briscoe - Tempe AZ, US
Huinan Yu - Kildeer IL, US
Piotr Grodzinski - Rockville MD, US
Rong-Fong Huang - Fremone CA, US
Jeremy W. Burdon - Minneapolis MN, US
Nicholas J. Naclerio - Menlo Park CA, US
David Wilcox - Sun Lakes AZ, US

Assignee:

WATERS TECHNOLOGIES CORPORATION - Milford MA

International Classification:

G01N 30/02

US Classification:

73 2339

Abstract:

A micro-gas chromatograph column is formed by texturing a channel into a plurality of green-sheet layers, which are then sintered together to form a substantially monolithic structure. A thick-film paste may be added to the channel textured in the green-sheet layers to provide a porous plug sintered in the micro-gas chromatograph column in the substantially monolithic. A thermal conductivity detector is formed in the substantially monolithic structure by depositing a conductive thick-film paste on the surface of one of the green-sheet layers to define a resistor in an exit channel of the micro-gas chromatograph column.

US Patent:

61300012, Oct 10, 2000

Filed:

Jul 15, 1997

Appl. No.:

8/893116

Inventors:

Song Q. Shi - Phoenix AZ
Franky So - Tempe AZ
Hsing-Chung Lee - Calabasas CA
Cynthia Gorsuch Briscoe - Tempe AZ

Assignee:

Motorola, Inc. - Schaumburg IL

International Classification:

H05B 3314

US Classification:

428690

Abstract:

An organic EL device includes a cathode, an organic electroluminescent layer and an anode, laminated in sequence. The organic layer is composed of a continuous organic medium A. sub. x B. sub. y, where A and B are components capable of transporting electrons and holes, respectively, x represents the content of the A component with a value ranging from 0 adjacent the anode to 100% adjacent the cathode, and y represents the content of the B component with a value ranging from 0 adjacent the cathode to 100% adjacent the anode. The lifetime of the device is improved by the elimination of heterojunctions in the continuous organic medium and suppression of the re-crystallization tendency of the organic materials. At least one fluorescent dye or pigment is incorporated in the organic layer to improve efficiency and color of the luminescence.