Chien-Ping Liang from 879 Dublin Dr APT B, Richardson, TX 75080, Phone: 2147141242

Atherosclerosis Susceptibility Gene Locus 1 (Athsq1) And Atherosclerosis Susceptibility Gene Locus 2 (Athsq2)
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US Patent:

20030068673, Apr 10, 2003
Filed:

Jul 2, 2001
Appl. No.:

09/898554
Inventors:

Alan Tall - Cresskill NJ, US
Carrie Welch - Sleepy Hollow NY, US
Chien-Ping Liang - Richardson TX, US
International Classification:

C12P021/02
C12N005/06
C07K014/705
C07H021/04
US Classification:

435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:

This invention provides isolated nucleic acids encoding mammalian membrane-bound and soluble LOX-1 receptors. The invention also provides methods of identifying agents that inhibit the activity of a mammalian LOX-1 receptor. This invention further provides methods of preventing or treating atherosclerosis, heart disease or stroke in a subject which comprise reducing the activity of membrane-bound LOX-1 receptor.

Atherosclerosis Susceptibility Gene Locus 1(Athsq1) And Atherosclerosis Susceptibility Gene Locus 2 (Athsq2)
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US Patent:

20040267000, Dec 30, 2004
Filed:

Aug 30, 2004
Appl. No.:

10/482673
Inventors:

Alan Tall - Cresskill NJ, US
Carrie Welch - Sleepy Hollow NY, US
Chien-Ping Liang - Richardson TX, US
International Classification:

C12Q001/68
C07H021/04
C07K014/775
US Classification:

536/023200, 435/006000, 435/069100, 435/320100, 435/325000, 530/359000
Abstract:

This invention provides isolated nucleic acids encoding mammalian membrane-bound and soluble LOX-1 receptors. The invention also provides methods of identifying agents that inhibit the activity of a mammalian LOX-1 receptor. This invention further provides methods of preventing or treating atherosclerosis, heart disease or stroke in a subject which comprise reducing the activity of membrane-bound LOX-1 receptor.