Carl Franzblau

US Patent:

20060010012, Jan 12, 2006

Filed:

Apr 12, 2005

Appl. No.:

11/104222

Inventors:

Carl Franzblau - Newton MA, US
Jay Kaplan - Harrington Park NJ, US

International Classification:

G06Q 10/00

US Classification:

705002000

Abstract:

The present invention provides a system and method of providing personal and medical information in a portable manner. The present invention also allows the user to easily update and modify the information contained in the device. Briefly, a storage element, preferably having a standard computer interface, most preferably a USB port, is disclosed. Sets of data structures that allow the user to incorporate information about their medical history and profile are provided on the storage element. The data structures also allow the user to enter images, such as jpeg, tiff or bitmap files, to further augment their history. These data structure also allow the health care provider to quickly and easily access the relevant information in a timely and organized manner. The storage element also contains the required software application needed to view the data structures.

US Patent:

52179036, Jun 8, 1993

Filed:

May 15, 1990

Appl. No.:

7/523587

Inventors:

Phillip J. Stone - Chestnut Hill MA
Carl Franzblau - Newton MA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

G01N 2300
G01N 2306
G01N 3002
B01D 1503

US Classification:

436 57

Abstract:

A method for determining a connective tissue breakdown product in a body fluid from an animal includes steps of providing a standard comprising the breakdown product having a radioactive label, the standard having a known specific radioactivity, combining the standard and a sample of the body fluid, removing from the combined standard and sample a purified breakdown product fraction containing labelled breakdown product from the standard together with breakdown product from the sample, and measuring the specific radioactivity of the fraction as a measure of the quantity of the breakdown product in the sample. Also, methods for assessing a condition of a selected connective tissue in an animal in vivo, and for assessing in vivo a disease process that includes destruction of a specified connective tissue component, and for assessing in vivo the efficacy of a therapy for treatment of such a disease process, include the steps of the method for determining a connective tissue breakdown product.

US Patent:

53546628, Oct 11, 1994

Filed:

Mar 11, 1993

Appl. No.:

8/030680

Inventors:

Phillip J. Stone - Chestnut Hill MA
Carl Franzblau - Newton MA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

C12Q 100
G01N 3353

US Classification:

435 792

Abstract:

A method for determining the quantity of a connective tissue or muscle tissue breakdown product in a body fluid from an animal includes steps of providing a standard comprising the breakdown product having a label, the standard having a known specific activity, combining the standard and a sample of the body fluid, removing from the combined standard and sample a purified breakdown product fraction containing labelled breakdown product from the standard together with breakdown product from the sample, and measuring the specific radioactivity of the fraction as a measure of the quantity of the breakdown product in the sample. Also, methods for assessing, in a body fluid from an animal, the condition of a selected connective tissue or a muscle tissue in an animal, and for assessing a disease process that includes destruction of a specified connective tissue component or muscle tissue, and for assessing the efficacy of a therapy for treatment of such a disease process, include the steps of the method for determining the quantity of a tissue breakdown product.

US Patent:

52623033, Nov 16, 1993

Filed:

Oct 11, 1990

Appl. No.:

7/595451

Inventors:

Jean D. Sipe - Roslindale MA
Greta Knapschaefer - Malden MA
Wayne A. Gonnerman - Waltham MA
Carl Franzblau - Newton Highlands MA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

G01N 3353

US Classification:

435 75

Abstract:

The present invention provides ligand/anti-ligand assays for detecting and/or measuring adherent proteins, including lipophilic serum or plasma proteins, such as serum amyloid A (SAA) and apolipoprotein A1 (apoA1); cytokines such as IL-1 beta, IL-6, and TNF alpha; pentraxins, such as CRP; and globular serum or plasma proteins such as albumin.

US Patent:

50321315, Jul 16, 1991

Filed:

Mar 2, 1988

Appl. No.:

7/163515

Inventors:

James E. Aysta - Stillwater MN
John T. Capecchi - Oakdale MN
Carl Franzblau - Newton MA
Donald F. Gibbons - North Oaks MN
Randall L. Knoll - Mahtomedi MN
Howard M. Leibowitz - Weston MA
Vickery Trinkaus-Randall - Maynard MA

Assignee:

Minnesota Mining and Manufacturing Company - St. Paul MN

International Classification:

C12N 500

US Classification:

623 66

Abstract:

A holding device for seeding cells on a surface of a prosthesis including chamber means for partially defining a first chamber with the first surface, and sealing means for providing a seal between the chamber means and the prosthesis so as to isolate the seeding surface from another portion of the prosthesis.

US Patent:

45657840, Jan 21, 1986

Filed:

Dec 7, 1983

Appl. No.:

6/558977

Inventors:

Carl Franzblau - Newton MA
Barbara A. Faris - Squantum MA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

C12N 500
C12R 191

US Classification:

435240

Abstract:

A method of growing anchorage-dependent cells is disclosed in which a substrate comprising a hydrogel is employed. The hydrogel is formed from an aqueous solution gelled with a crosslinked polymer of a hydrophilic monomer and includes a macromolecule capable of supporting cell growth.

US Patent:

55366406, Jul 16, 1996

Filed:

Oct 29, 1993

Appl. No.:

8/146574

Inventors:

Jean D. Sipe - Roslindale MA
Greta Knapschaefer - Malden MA
Wayne A. Gonnerman - Waltham MA
Carl Franzblau - Newton Highlands MA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

G01N 3353

US Classification:

435 75

Abstract:

The present invention provides ligand/anti-ligand assays for detecting and/or measuring adherent proteins, including lipophilic serum or plasma proteins, such as serum amyloid A (SAA) and apolipoprotein Al (apoAl); cytokines such as IL-1 beta, IL-6, and TNF alpha; pentraxins, such as CRP; and globular serum or plasma proteins such as albumin.

US Patent:

54892619, Feb 6, 1996

Filed:

Sep 12, 1994

Appl. No.:

8/304168

Inventors:

Carl Franzblau - Newton MA
Barbara A. Faris - Squantum MA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

A61F 1300

US Classification:

602 41

Abstract:

A method of growing anchorage-dependent cells is disclosed in which a substrate includes a hydrogel is employed. The hydrogel is formed from an aqueous solution gelled with a crosslinked polymer of a hydrophilic monomer and includes a macromolecule capable of supporting cell growth.

Author:

Carl Franzblau

ISBN #:

0306390795