Chris A. Buhr - Redwood City CA, US Katherine Lara - San Mateo CA, US Sunghoon Ma - Foster City CA, US Longcheng Wang - Palo Alto CA, US Bryan K.S. Yeung - San Francisco CA, US
Assignee:
Exelixis, Inc - South San Francisco CA
International Classification:
A61K 31/5377 C07D 471/04 A61K 31/519
US Classification:
5142342, 544279, 51426411, 544117, 51425216
Abstract:
The invention is directed to Compounds of Formula I and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.
Chris A. Buhr - Redwood City CA, US Katherine Lara - San Mateo CA, US Sunghoon Ma - Foster City CA, US Morrison Mac - San Francisco CA, US John M. Nuss - Danville CA, US Longcheng Wang - Palo Alto CA, US Yong Wang - Foster City CA, US Bryan K.S. Yeung - San Francisco CA, US
Assignee:
Exelixix, Inc. - South San Francisco CA
International Classification:
A61K 31/519 C07D 471/04 A61P 35/00
US Classification:
51426411, 544279
Abstract:
The invention is directed to Compounds of Formula I:and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.
Chris Buhr - Redwood City CA, US Sunghoon Ma - Foster City CA, US John Nuss - Danville CA, US Zerom Tesfai - Castro Valley CA, US Longcheng Wang - Palo Alto CA, US Bryan Yeung - San Francisco CA, US
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.
Brian Yeung (1989-1992), Phil Gates (1974-1977), Patrick Curran (1983-1986), Bob Ross (1949-1953), Keith Metzger (1983-1985), Jennifer Wyckoff (1983-1985)
Brian Yeung (1992-1996), Jennifer Kamian (1986-1990), Karl Hubbell (1985-1989), Ben Grover (1995-1999), Mike Foley (1979-1983), Christina Adranly (2000-2004)