Blair Ardman

US Patent:

6997863, Feb 14, 2006

Filed:

Jul 19, 2002

Appl. No.:

10/200082

Inventors:

Erik S. Handy - Arlington MA, US
Robert Ivkov - Marblehead MA, US
Diane Ellis-Busby - Lancaster MA, US
Allan Foreman - Epping NH, US
Susan J. Braunhut - Wellesley MA, US
Douglas U. Gwost - Shoreview MN, US
Blair Ardman - Marblehead MA, US

Assignee:

Triton BioSystems, Inc. - Chelmsford MA

International Classification:

A61N 2/00

US Classification:

600 9, 977DIG 1

Abstract:

Disclosed are therapeutic methods for the treatment of disease material involving administration of a thermotherapeutic magnetic composition, which contains single-domain magnetic particles attached to a target-specific ligand, to a patient and application of an alternating magnetic field to inductively heat the thermotherapeutic magnetic composition. Also disclosed are methods of administering the thermotherapeutic magnetic material composition. The thermotherapeutic methods may be used where the predetermined target is associated with diseases, such as cancer, diseases of the immune system, and pathogen-borne diseases, and undesirable targets, such as toxins, reactions associated with organ transplants, hormone-related diseases, and non-cancerous diseased cells or tissue.

US Patent:

52525562, Oct 12, 1993

Filed:

Mar 30, 1990

Appl. No.:

7/503458

Inventors:

Blair Ardman - Brookline MA

Assignee:

New England Medical Center Hospitals, Inc. - Boston MA

International Classification:

A61K 3900

US Classification:

514 8

Abstract:

A fragment capable of binding to an anti-CD43 autoantibody made by a human infected with HIV-1. The fragment, which includes a part or the entirety of an amino acid sequence corresponding to positions 20-254 of CD43, can be used in treatment or diagnosis of HIV-1 infections.