Barbara L Mericle

US Patent:

20030138438, Jul 24, 2003

Filed:

Apr 5, 2002

Appl. No.:

10/117982

Inventors:

Barbara Mericle - Edmonds WA, US
Gary Fanger - Mill Creek WA, US
Thomas Vedvick - Federal Way WA, US
Darrick Carter - Seattle WA, US
Yoshihiro Watanabe - Mercer Island WA, US
Robert Henderson - Edmonds WA, US
Michael Kalos - Seattle WA, US
A. Spies - Shoreline WA, US
Teresa Foy - Federal Way WA, US
Liqun Fan - Bellevue WA, US
Tongtong Wang - Medina WA, US

Assignee:

Corixa Corporation - Seattle WA

International Classification:

A61K039/00

US Classification:

424/185100, 424/277100

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.