Baolong Zhu from Johnston, IA, age 60

Us Patents

Pesticidally Active Proteins And Polynucleotides Obtainable From Species
view source
US Patent:

7902334, Mar 8, 2011
Filed:

Jul 10, 2007
Appl. No.:

11/775663
Inventors:

Scott B. Bintrim - Westfield IN, US
Scott A. Bevan - Indianapolis IN, US
Baolong Zhu - San Diego CA, US
Donald J. Merlo - Carmel IN, US
Assignee:

Dow AgroSciences LLC - Indianapolis IN
International Classification:

C07K 14/00
US Classification:

530350, 506 7, 506 13
Abstract:

The subject invention provides unique biological alternatives for pest control. More specifically, the present invention relates to novel pesticidal proteins, novel sources of pesticidal proteins, polynucleotides that encode such toxins, and to methods of using these toxins to control insects and other plant pests. The subject invention relates to the surprising discovery that species, and proteins therefrom, have toxicity to lepidopterans. There have been no known reports of a species, strain, or protein having toxicity to lepidopterans. This is also the first known example of a Cry protein that is toxic to lepidopterans. Furthermore, this is the first known report of a having toxin complex (TC)-like proteins. The DAS1529 isolate disclosed here is also the first known example of a natural bacterium that produces both a Cry toxin and TC proteins. The subject invention also relates to new classes of Cry and TC proteins that are pesticidally active.

Methods Of Inhibiting Insects By Treatment With A Complex Comprising A Insecticidal Protein And One Or Two Enhancer Proteins
view source
US Patent:

8084418, Dec 27, 2011
Filed:

Feb 16, 2009
Appl. No.:

12/371825
Inventors:

Timothy D. Hey - Zionsville IN, US
Amanda D. Schleper - Westfield IN, US
Scott A. Bevan - Indianapolis IN, US
Scott B. Bintrim - Westfield IN, US
Jon C. Michell - West Lafayette IN, US
Ze Sheng Li - Westfield IN, US
Weiting Ni - Carmel IN, US
Baolong Zhu - San Diego CA, US
Donald J. Merlo - Carmel IN, US
Thomas Meade - Zionsville IN, US
Assignee:

Dow AgroSciences LLC - Indianapolis IN
International Classification:

A01N 33/04
A01N 25/00
A61K 38/16
C07K 14/195
US Classification:

514 45, 424405, 514 212, 530350
Abstract:

The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from , and , can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from , or , for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone protein toxin as well as a stand-alone protein toxin. (As one skilled in the art knows, toxin proteins tend to be more desirable for controlling lepidopterans while toxin proteins tend to be more desirable for controlling coleopterans. ) This reduces the number of genes, and transformation events, needed to be expressed by a transgenic plant to achieve effective control of a wider spectrum of target pests.

Pesticidally Active Proteins And Polynucleotides Obtainable From Paenibacillus Species
view source
US Patent:

20040110184, Jun 10, 2004
Filed:

Jun 27, 2003
Appl. No.:

10/609113
Inventors:

Scott Bintrim - Westfield IN, US
Scott Bevan - Indianapolis IN, US
Baolong Zhu - San Diego CA, US
Donald Merlo - Carmel IN, US
Assignee:

Dow AgroSciences LLC - Indianapolis IN
International Classification:

C12Q001/68
G01N033/554
G01N033/569
US Classification:

435/006000, 435/007320
Abstract:

The subject invention provides unique biological alternatives for pest control. More specifically, the present invention relates to novel pesticidal proteins, novel sources of pesticidal proteins, polynucleotides that encode such toxins, and to methods of using these toxins to control insects and other plant pests. The subject invention relates to the surprising discovery that Paenibacillus species, and proteins therefrom, have toxicity to lepidopterans. There have been no known reports of a Paenibacillus species, strain, or protein having toxicity to lepidopterans. This is also the first known example of a Paenibacillus Cry protein that is toxic to lepidopterans. Furthermore, this is the first known report of Paenibacillus having toxin complex (TC)-like proteins. The DASisolate disclosed here is also the first known example of a natural bacterium that produces both a Cry toxin and TC proteins. The subject invention also relates to new classes of Cry and TC proteins that are pesticidally active.

Mixing And Matching Tc Proteins For Pest Control
view source
US Patent:

20040208907, Oct 21, 2004
Filed:

Jan 7, 2004
Appl. No.:

10/754115
Inventors:

Timothy Hey - Zionsville IN, US
Amanda Schleper - Westfield IN, US
Scott Bevan - Indianapolis IN, US
Scott Bintrim - Westfield IN, US
Jon Mitchell - West Lafayette IN, US
Ze Li - Westfield IN, US
Weiting Ni - Carmel IN, US
Baolong Zhu - San Diego CA, US
Donald Merlo - Carmel IN, US
Thomas Meade - Zionsville IN, US
Assignee:

Dow AgroSciences, LLC - Indianapolis IN
International Classification:

A01N025/00
A01N063/00
US Classification:

424/405000, 514/012000
Abstract:

The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from and can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from or for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone protein toxin as well as a stand-alone protein toxin. (As one skilled in the art knows, toxin proteins tend to be more desirable for controlling lepidopterans while toxin proteins tend to be more desirable for controlling coleopterans.) This reduces the number of genes, and transformation events, needed to be expressed by a transgenic plant to achieve effective control of a wider spectrum of target pests. Certain preferred combinations of heterologous TC proteins are also disclosed herein. Other objects, advantages, and features of the subject invention will be apparent to one skilled in the art having the benefit of the subject disclosure.

Methane Monooxygenase Enzymes
view source
US Patent:

20210403883, Dec 30, 2021
Filed:

Aug 30, 2021
Appl. No.:

17/461102
Inventors:

- Alameda CA, US
Derek Lorin Greenfield - Kensington CA, US
Noah Charles Helman - El Cerrito CA, US
Stephanie Rhianon Jones - Berkeley CA, US
Baolong Zhu - Johnston IA, US
International Classification:

C12N 9/02
C12N 15/70
C12N 15/75
C12N 15/77
Abstract:

Improved soluble methane monooxygenases and soluble methane monooxygenase systems are provided.

Improved Methane Monooxygenase Enzymes
view source
US Patent:

20200172881, Jun 4, 2020
Filed:

Jul 6, 2018
Appl. No.:

16/629018
Inventors:

- Alameda CA, US
Derek Lorin GREENFIELD - Kensington CA, US
Noah Charles HELMAN - El Cerrito CA, US
Stephanie Rhianon JONES - Evanston IL, US
Baolong ZHU - Zionsville IN, US
International Classification:

C12N 9/02
C12N 15/70
C12N 15/75
C12N 15/77
Abstract:

Improved soluble methane monooxygenases and soluble methane monooxygenase systems are provided.

Novel Car Enzymes And Improved Production Of Fatty Alcohols
view source
US Patent:

20200109374, Apr 9, 2020
Filed:

May 16, 2019
Appl. No.:

16/414550
Inventors:

- South San Francisco CA, US
Elizabeth J. Clarke - South San Francisco CA, US
Eli S. Groban - South San Francisco CA, US
Vikranth Arlagadda - South San Francisco CA, US
Sungwon Lee - South San Francisco CA, US
Xuezhi Li - South San Francisco CA, US
Zhihao Hu - South San Francisco CA, US
Baolong Zhu - South San Francisco CA, US
International Classification:

C12N 9/02
C12P 7/04
Abstract:

The disclosure relates to variant carboxylic acid reductase (CAR) enzymes for the improved production of fatty alcohols in recombinant host cells.

Culture Modified To Convert Methane Or Methanol To 3-Hydroxyproprionate
view source
US Patent:

20200048639, Feb 13, 2020
Filed:

Feb 17, 2018
Appl. No.:

16/486459
Inventors:

- Emeryville CA, US
Derek Lorin GREENFIELD - Kensington CA, US
Noah Charles HELMAN - El Cerrito CA, US
Stephanie Rhianon JONES - Berkeley CA, US
Baolong ZHU - San Diego CA, US
International Classification:

C12N 15/52
C12P 7/42
C12N 9/02
Abstract:

Provided are engineered organisms which can convert methane or methanol to 3-hydroxypropionate.