Reiner L. Gentz - Rockville MD Arvind Chopra - Gaithersburg MD Parveen Kaushal - Silver Springs MD Thomas Spitznagel - Vienna VA Edward Unsworth - Kensington MD Fazal Khan - Gaithersburg MD
Assignee:
Human Genome Sciences, Inc. - Rockville MD
International Classification:
A61K 3818
US Classification:
514 12, 514 2, 424 851
Abstract:
The invention is directed to liquid and lyophilized forms of Keratinocyte Growth Factor-2 (KGF-2) and derivatives thereof. This invention further relates to the formulation of KGF-2 for therapeutic use, for example, to promote or accelerate wound healing.
Human B-Cell Translocation Genes-2 And 3 Antibodies
The present invention relates to antiproliferative genes. More specifically, isolated nucleic acid molecules are provided encoding the human B-cell translocation genes 2 and 3 (BTG-2 and BTG-3). BTG-2 and BTG-3 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies to BTG-2 and BGT-3.
Reiner L. Gentz - Rockville MD, US Arvind Chopra - Gaithersburg MD, US Parveen Kaushal - Silver Spring MD, US Thomas Spitznagel - Vienna VA, US Edward Unsworth - Kensington MD, US Fazal Khan - Gaithersburg MD, US
The invention is directed to liquid and lyophilized forms of Keratinocyte Growth Factor-2 (KGF-2) and derivatives thereof. This invention further relates to the formulation of KGF-2 for therapeutic use, for example, to promote or accelerate wound healing.
Diagnostic Methods Based On Human Btg-2 And Btg-3 Polypeptides
Charles A. Kunsch - Norcross GA, US Arvind Chopra - Gaithersburg MD, US Craig A. Rosen - Laytonsville MD, US
Assignee:
Human Genome Sciences, Inc. - Rockville MD
International Classification:
G01N 33/53 C07K 14/00 A61K 38/17
US Classification:
435 71, 514 21, 530350, 436501
Abstract:
The present invention relates to novel antiproliferative genes. More specifically, isolated nucleic acid molecules are provided encoding the human B-cell translocation genes 2 and 3 (BTG-2 and BTG-3). BTG-2 and BTG-3 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same.
The present invention relates to a novel connective tissue growth factor-3 protein which is a member of the growth factor superfamily. In particular, isolated nucleic acid molecules are provided encoding the human connective tissue growth factor-3 protein. Connective tissue growth factor-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic and therapeutic methods for detecting and treating connective tissue related disorders.
Reinhard Ebner - Gaithersburg MD, US Arvind Chopra - Gaithersburg MD, US Steven M. Ruben - Brookeville MD, US
Assignee:
Human Genome Sciences, Inc. - Rockville MD
International Classification:
C07K 14/475 C07K 19/00
US Classification:
530350, 530324, 530395, 435 691
Abstract:
The present invention relates to a novel connective tissue growth factor-3 protein which is a member of the growth factor superfamily. In particular, isolated nucleic acid molecules are provided encoding the human connective tissue growth factor-3 protein. Connective tissue growth factor-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic and therapeutic methods for detecting and treating connective tissue related disorders.
Myelin Oligodendrocyte Glycoprotein-Like Protein (Mogp)
Arvind Chopra - Gaithersburg MD, US Henrik Olsen - Gaithersburg MD, US Reiner Gentz - Rockville MD, US Steven Ruben - Olney MD, US
Assignee:
Human Genome Sciences, Inc.
International Classification:
C07H021/02 C07H021/04
US Classification:
536/023100
Abstract:
The present invention relates to a novel MOGp protein which is a member of the Ig superfamily. In particular, isolated nucleic acid molecules are provided encoding the human MOGp protein. MOGp polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic and therapeutic methods for detecting and treating cancer, inflammation, and multiple sclerosis (MS).
Reiner Gentz - Belo Horizonte-Mg, BR Arvind Chopra - Gaithersburg MD, US Parveen Kaushal - Silver Spring MD, US Thomas Spitznagel - Vienna VA, US Edward Unsworth - Kensington MD, US Fazal Khan - Gaithersberg MD, US
Assignee:
Human Genome Sciences, Inc. - Rockville MD
International Classification:
A61K038/18
US Classification:
514/012000
Abstract:
The invention is directed to liquid and lyophilized forms of Keratinocyte Growth Factor-2 (KGF-2) and derivatives thereof. This invention further relates to the formulation of KGF-2 for therapeutic use, for example, to promote or accelerate wound healing.
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