Anthony M Cocuzza

US Patent:

6489320, Dec 3, 2002

Filed:

Sep 7, 2000

Appl. No.:

09/657518

Inventors:

Anthony J. Cocuzza - Wilmington DE
James D. Rodgers - Landenberg PA

Assignee:

Bristol-Myers Squibb Pharma Company - Princeton NJ

International Classification:

A61K 3155

US Classification:

51421105, 540488, 540490

Abstract:

The present invention relates to benzoxazepinones of formula I: or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same and methods of using the same for treating viral infection or as an assay standard or reagent.

US Patent:

20110072398, Mar 24, 2011

Filed:

Sep 21, 2009

Appl. No.:

12/563322

Inventors:

Anthony M. Cocuzza - Poughkeepsie NY, US
Shayne Grant - Research Triangle Park NC, US
Pu Liu - Endicott NY, US

Assignee:

INTERNATIONAL BUSINESS MACHINES CORPORATION - Armonk NY

International Classification:

G06F 3/048

US Classification:

715853

Abstract:

A method comprises creating a first node, determining whether an indicator associated with a head node is present, and designating the first node as a head node, defining and associating a head node identifier with the first node, define a link from the first node to the first node, and create and save an indicator associated with the head node responsive to determining that the indicator associated with a head node is not present.

US Patent:

45059055, Mar 19, 1985

Filed:

Apr 15, 1982

Appl. No.:

6/368877

Inventors:

George A. Boswell - Wilmington DE
Anthony J. Cocuzza - Wilmington DE

Assignee:

E. I. Du Pont de Nemours and Company - Wilmington DE

International Classification:

C07C14940
A61K 31215

US Classification:

514150

Abstract:

Certain 7-oxobicyclo[3. 2. 0] hept-2-en-2-carboxylic acids, esters, and salts thereof useful as antibacterial agents or as intermediates for antibacterial agents, and methods for making and using them.

US Patent:

50475193, Sep 10, 1991

Filed:

Jun 12, 1987

Appl. No.:

7/057565

Inventors:

Frank W. Hobbs - Wilmington DE
Anthony J. Cocuzza - Wilmington DE

Assignee:

E. I. Du Pont de Nemours and Company - Wilmington DE

International Classification:

C07H 100

US Classification:

536 23

Abstract:

Alkynylamino-nucleotides and labeled alkynylamino-nucleotides useful, for example, as chain terminating substrates for DNA sequencing are provided along with several key intermediates and processes for their preparation.

US Patent:

45902747, May 20, 1986

Filed:

Jan 3, 1985

Appl. No.:

6/688382

Inventors:

Anthony J. Cocuzza - Wilmington DE

Assignee:

E. I. Du Pont de Nemours and Company - Wilmington DE

International Classification:

C07D29502
A61K 31495

US Classification:

544396

Abstract:

Antihypertensive piperazineethylidenebenzocycloalkanes are provided. These compounds have the formula: ##STR1## wherein R. sub. 1, R. sub. 2 and R. sub. 3 are independently C. sub. 1 -C. sub. 6 alkyl, hydrogen, C. sub. 1 -C. sub. 6 alkoxy, hydroxy, or halo, or R. sub. 1 and R. sub. 2 or R. sub. 2 and R. sub. 3 together can form a methylenedioxy bridge; R. sub. 4 is H or C. sub. 1 -C. sub. 6 alkyl; n is 0, 1 or 2; m is 0, 1, 2 or 3; and Ar. sub. 1 and Ar. sub. 2 are independently phenyl optionally substituted with one or two of halogen, hydroxy, or C. sub. 1 -C. sub. 6 alkoxy groups, or a pharmaceutically acceptable salt thereof.

US Patent:

54847010, Jan 16, 1996

Filed:

Jan 31, 1992

Appl. No.:

7/829857

Inventors:

Anthony J. Cocuzza - Wilmington DE
Frank W. Hobbs - Wilmington DE
Robert J. Zagursky - Wilmington DE
Neil A. Straus - North York, CA

Assignee:

E. I. Du Pont de Nemours and Company - Wilmington DE

International Classification:

C12Q 168
C12P 1934

US Classification:

435 6

Abstract:

A simplified method for isolating primer extension products and generating them in a form appropriate for electrophoresis is disclosed. The method is compatible with automated DNA sequencing procedures.

US Patent:

61403202, Oct 31, 2000

Filed:

Sep 1, 1998

Appl. No.:

9/145101

Inventors:

Anthony J. Cocuzza - Wilmington DE
James D. Rodgers - Landenberg PA

Assignee:

Dupont Pharmaceuticals Company - Wilmington DE

International Classification:

A61K 3155
A61P 3118
C07D26708

US Classification:

51421105

Abstract:

The present invention relates to benzoxazepinones of formula I: ##STR1## or stereoisomeric forms or mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same and methods of using the same for treating viral infection or as an assay standard or reagent.

US Patent:

49084534, Mar 13, 1990

Filed:

Jan 23, 1989

Appl. No.:

7/300504

Inventors:

Anthony J. Cocuzza - Wilmington DE

Assignee:

E. I. Du Pont De Nemours and Company - Wilmington DE

International Classification:

C07F 965

US Classification:

548113

Abstract:

Reagents useful in the preparation of 5'-biotinylated oligonucleotides are disclosed.